ERK and Akt exhibit distinct signaling responses following stimulation by pro-angiogenic factors

ERK and Akt exhibit distinct signaling responses following stimulation by pro-angiogenic factors

Background: Angiogenesis plays an important role in the survival of tissue, such as blood vessels deliver oxygen and nutrients needed by the cells of the population. Thus, targeting angiogenesis is a prominent strategy in a variety of settings, including both tissue engineering and cancer treatment. However, not all approaches that modulate angiogenesis lead to a successful outcome. angiogenesis based therapies primarily targeting pro-angiogenic factors such as vascular endothelial growth factor-A (VEGF) or fibroblast growth factor (FGF) in isolation, and there is a limited understanding of how these promoters combine together to stimulate angiogenesis. Target one pathway could be enough, because the alternative pathways can compensate, reducing the overall effect of a treatment strategy.


Methods: To gain insight into the mechanistic and identify new therapeutic strategy, we have developed a detailed mathematical models to quantitatively characterize crosstalk of FGF and VEGF intracellular signaling. The model focuses on FGF- and VEGF-induced MAPK (MAPK) signaling to promote cell proliferation and phosphatidylinositol 3-kinase / protein kinase B (PI3K / Akt) pathway, which promotes cell survival and migration. We fit the model for experimental datasets published the size of phosphorylated extracellular regulated kinase (perk) and Akt (pAkt) on FGF or VEGF stimulation. We validate the model with a separate set of data.


Results: We apply mathematical models are trained and validated to characterize the dynamics of Perk and pAkt in response to mono and co-stimulation by FGF and VEGF. The model predicts that for a certain range of ligand concentration, maximum Perk level is more responsive to changes in ligand concentration compared with the maximum level of pAkt. Also, the combination of FGF and VEGF showed a greater effect in increasing the maximum perk than the sum of the individual effects, which are not visible to the maximum pAkt levels. In addition, we identify the model and kinetic parameters affect the species that specifically modulate Perk and pAkt response, which is a potential target for the treatment of angiogenesis-based.


Conclusion: Overall, the model predicts the effect of a combination of FGF and VEGF stimulation on ERK and Akt quantitative and provides a framework for the mechanic to explain experimental results and guide experimental design. Thus, this model can be used to study the effects of the therapy pro- and anti-angiogenic primarily targeting ERK and / or activation of Akt on stimulation with FGF and VEGF. Video Abstract.

 ERK and Akt exhibit distinct signaling responses following stimulation by pro-angiogenic factors
ERK and Akt exhibit distinct signaling responses following stimulation by pro-angiogenic factors

TGF-β3 Pressing melanogenesis in cultured human melanocytes with neighboring cells and UV-irradiated human skin

Background: Ultraviolet radiation (UVR) is the most well-known causes of skin pigmentation is accompanied with photoaging. Transforming growth factor (TGF) -β1 shown previously have anti-melanogenic property; However, it can cause scarring in the skin.
Objective: We investigated the effect of TGF-β3 on melanogenesis in cultured human melanocytes in the skin constituent cells UV-irradiated and UV-irradiated human skin.


Methods: UVB radiation or treatment with stem cell factor (SCF) and endothelin-1 (ET-1) was applied to human melanocytes cocultured with keratinocytes and / or fibroblasts and ex vivo human skin. mechanistic pathways are further explored after treatment with TGF-β3.


Results: While UVB radiation or SCF / ET-1 enhanced melanogenesis, TGF-β3 accumulation effectively inhibits melanin and tyrosinase activity through downregulation of extracellular signal-regulated kinase (ERK) / microphthalmia associated transcription factor (MITF) pathway. TGF-β3 increased expression of keratinocyte differentiation markers.

FGF13 siRNA

20-abx901944
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  • 15 nmol
  • 30 nmol

FGF13, Peptide

43-178P 0.1 mg
EUR 405.6

FGF13 Antibody

35216 100ul
EUR 319

FGF13 Antibody

35216-100ul 100ul
EUR 302.4

FGF13 Antibody

35216-50ul 50ul
EUR 224.4

FGF13 Antibody

E035216 100μg/100μl
EUR 255
Description: Available in various conjugation types.

FGF13 Antibody

E19-4699 100μg/100μl
EUR 225
Description: Available in various conjugation types.

FGF13 Antibody

E11-20772C 100μg
EUR 225
Description: Available in various conjugation types.

FGF13 Antibody

E93861 100μg
EUR 255
Description: Available in various conjugation types.

FGF13 Antibody

DF4699 200ul
EUR 420

FGF13 Antibody

DF4699-100ul 100ul
EUR 280

FGF13 Antibody

DF4699-200ul 200ul
EUR 350

FGF13 Antibody

E306653 200ul
EUR 275
Description: Available in various conjugation types.

FGF13 Antibody

E38PA4903 100ul
EUR 225
Description: Available in various conjugation types.

FGF13 Antibody

1-CSB-PA008241
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  • 100ug
  • 50ug
Description: A polyclonal antibody against FGF13. Recognizes FGF13 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000

FGF13 Antibody

1-CSB-PA008619ESR1HU
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  • 100ul
  • 50ul
Description: A polyclonal antibody against FGF13. Recognizes FGF13 from Human, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200

FGF13 Antibody

1-CSB-PA008619ESR2HU
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  • 100ul
  • 50ul
Description: A polyclonal antibody against FGF13. Recognizes FGF13 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

FGF13 Antibody

1-CSB-PA008619GA01HU
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  • 150ul
  • 50ul
Description: A polyclonal antibody against FGF13. Recognizes FGF13 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

FGF13 Antibody

1-CSB-PA008619LA01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against FGF13. Recognizes FGF13 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

FGF13 antibody

70R-17291 50 ul
EUR 289
Description: Rabbit polyclonal FGF13 antibody

FGF13 antibody

70R-9323 50 ug
EUR 467
Description: Affinity purified rabbit polyclonal FGF13 antibody

FGF13 antibody

70R-6208 50 ug
EUR 467
Description: Rabbit polyclonal FGF13 antibody raised against the middle region of FGF13

FGF13 Antibody

ABD13096 100 ug
EUR 525.6

FGF13 Antibody

ABD4699 100 ug
EUR 525.6

FGF13 Antibody

CAC08436-100ug 100ug
EUR 314

FGF13 Antibody

CAC08436-50ug 50ug
EUR 199.2

FGF13 Antibody

CSB-PA151977- each
EUR 402
Description: A polyclonal antibody against FGF13. Recognizes FGF13 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

FGF13 Antibody

CSB-PA151977-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against FGF13. Recognizes FGF13 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

FGF13 Antibody

GWB-MT832D 50ug Ask for price

FGF13 Antibody

GWB-MT833E 50ug Ask for price

FGF13 Antibody

R34447-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Fibroblast growth factor 13

FGF13 Rabbit pAb

E2507895 100ul
EUR 225
Description: Available in various conjugation types.

FGF13 Rabbit pAb

A7895-100ul 100 ul
EUR 369.6

FGF13 Rabbit pAb

A7895-200ul 200 ul
EUR 550.8

FGF13 Rabbit pAb

A7895-20ul 20 ul
EUR 219.6

FGF13 Rabbit pAb

A7895-50ul 50 ul
EUR 267.6

anti- FGF13 antibody

FNab03090 100µg
EUR 606.3
Description: Antibody raised against FGF13

Fgf13 (untagged) - Mouse fibroblast growth factor 13 (Fgf13), (10ug)

MC208481 10 µg Ask for price

FGF13 cloning plasmid

CSB-CL008619HU-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the FGF13 gene.

FGF13 Blocking Peptide

33R-7175 100 ug
EUR 119
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of FGF13 antibody, catalog no. 70R-9323

FGF13 Blocking Peptide

33R-9144 100 ug
EUR 119
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of FGF13 antibody, catalog no. 70R-6208

FGF13 Blocking Peptide

DF4699-BP 1mg
EUR 234

FGF13 Blocking Peptide

20-abx162114
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  • 1 mg
  • 5 mg

FGF13 Polyclonal Antibody

E97895 100ul
EUR 225
Description: Available in various conjugation types.

FGF13 Polyclonal Antibody

A59126
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  • 100 µg
  • 20 ul
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  • 100 ul

Polyclonal FGF13 Antibody

APR05426G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human FGF13 . This antibody is tested and proven to work in the following applications:

FGF13 Conjugated Antibody

C35216 100ul
EUR 476.4

FGF13 Polyclonal Antibody

A71990 50 μl
EUR 408

FGF13 Polyclonal Antibody

E-AB-19868-120uL 120uL
EUR 240
Description: Unconjugated

FGF13 Polyclonal Antibody

E-AB-19868-200uL 200uL
EUR 399
Description: Unconjugated

FGF13 Polyclonal Antibody

E-AB-19868-20uL 20uL
EUR 73
Description: Unconjugated

FGF13 Polyclonal Antibody

E-AB-19868-60uL 60uL
EUR 143
Description: Unconjugated

FGF13 Polyclonal Antibody

E-AB-62743-120uL 120uL
EUR 320
Description: Unconjugated

FGF13 Polyclonal Antibody

E-AB-62743-200uL 200uL
EUR 530
Description: Unconjugated

FGF13 Polyclonal Antibody

E-AB-62743-60uL 60uL
EUR 200
Description: Unconjugated

FGF13 Polyclonal Antibody

E-AB-62743-each each Ask for price
Description: Unconjugated

FGF13 Polyclonal Antibody

E-AB-17962-120uL 120uL
EUR 240
Description: Unconjugated

FGF13 Polyclonal Antibody

E-AB-17962-200uL 200uL
EUR 399
Description: Unconjugated

FGF13 Polyclonal Antibody

E-AB-17962-20uL 20uL
EUR 73
Description: Unconjugated

FGF13 Polyclonal Antibody

E-AB-17962-60uL 60uL
EUR 143
Description: Unconjugated

Fgf13 (GFP-tagged) - Mouse fibroblast growth factor 13 (Fgf13), (10ug)

MG221854 10 µg Ask for price

Fgf13 (Myc-DDK-tagged) - Mouse fibroblast growth factor 13 (Fgf13)

MR221854 10 µg Ask for price

Fgf13 (untagged ORF) - Rat fibroblast growth factor 13 (Fgf13), (10 ug)

RN201615 10 µg Ask for price

FGF13 ELISA KIT|Human

EF009617 96 Tests
EUR 826.8

Rat FGF13 shRNA Plasmid

20-abx986958
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  • 150 µg
  • 300 µg

Human FGF13 shRNA Plasmid

20-abx951578
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  • 150 µg
  • 300 µg

FGF13 (Isoform 1) Antibody

abx431249-200ul 200 ul
EUR 460.8

Mouse FGF13 shRNA Plasmid

20-abx970317
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  • 150 µg
  • 300 µg

FGF13 (Isoform 1) Antibody

abx431249-200l 200 µl
EUR 387.5

FGF13 (untagged)-Human fibroblast growth factor 13 (FGF13), transcript variant 4

SC325591 10 µg Ask for price

FGF13 (untagged)-Human fibroblast growth factor 13 (FGF13), transcript variant 3

SC325627 10 µg Ask for price

FGF13 (untagged)-Human fibroblast growth factor 13 (FGF13), transcript variant 5

SC325628 10 µg Ask for price

FGF13 (untagged)-Human fibroblast growth factor 13 (FGF13), transcript variant 2

SC325675 10 µg Ask for price

FGF13 (untagged)-Human fibroblast growth factor 13 (FGF13), transcript variant 1

SC109226 10 µg Ask for price

FGF13 (untagged)-Human fibroblast growth factor 13 (FGF13), transcript variant 6

SC305664 10 µg Ask for price

Fgf13 (untagged) - Mouse fibroblast growth factor 13 (Fgf13), transcript variant 3

MC226197 10 µg Ask for price

Fgf13 (untagged) - Mouse fibroblast growth factor 13 (Fgf13), transcript variant 2

MC226608 10 µg Ask for price

FGF13 (untagged)-Human fibroblast growth factor 13 (FGF13), transcript variant 1

SC320392 10 µg Ask for price

FGF13 Antibody, HRP conjugated

1-CSB-PA008619LB01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against FGF13. Recognizes FGF13 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

FGF13 Antibody, FITC conjugated

1-CSB-PA008619LC01HU
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  • 100ug
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Description: A polyclonal antibody against FGF13. Recognizes FGF13 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

OACD03502-1ML - FGF13 Antibody

OACD03502-1ML 1ml
EUR 669

OACD03503-1ML - FGF13 Antibody

OACD03503-1ML 1ml
EUR 669

OACD03504-1ML - FGF13 Antibody

OACD03504-1ML 1ml
EUR 729

OACA07424-50UL - FGF13 Antibody

OACA07424-50UL 50ul
EUR 189

OACA07425-50UL - FGF13 Antibody

OACA07425-50UL 50ul
EUR 189

OAAN02496-50UL - FGF13 Antibody

OAAN02496-50UL 50ul
EUR 149

OACA02969-50UG - FGF13 Antibody

OACA02969-50UG 50ug
EUR 179

FGF13 Antibody, Biotin conjugated

1-CSB-PA008619LD01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against FGF13. Recognizes FGF13 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

FGF13 Rabbit Polyclonal Antibody

55362 100ul
EUR 439

OACA07424-100UL - FGF13 Antibody

OACA07424-100UL 100ul
EUR 230

OACA07425-100UL - FGF13 Antibody

OACA07425-100UL 100ul
EUR 230

OAGA01439-100UL - FGF13 Antibody

OAGA01439-100UL 100ul
EUR 369

OAAN02496-100UL - FGF13 Antibody

OAAN02496-100UL 100ul
EUR 249

OAAN02496-200UL - FGF13 Antibody

OAAN02496-200UL 200ul
EUR 389

OACA02969-100UG - FGF13 Antibody

OACA02969-100UG 100ug
EUR 319

OACD03502-100UL - FGF13 Antibody

OACD03502-100UL 100ul
EUR 199

OACD03503-100UL - FGF13 Antibody

OACD03503-100UL 100ul
EUR 199

OACD03504-100UL - FGF13 Antibody

OACD03504-100UL 100ul
EUR 209

FGF13 Rabbit Polyclonal Antibody

E10G06520 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

FGF13 Rabbit Polyclonal Antibody

E10G13411 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

FGF13 Rabbit Polyclonal Antibody

E10G13770 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

FGF13 Rabbit Polyclonal Antibody

E10G06884 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

FGF13 (GFP-tagged) - Human fibroblast growth factor 13 (FGF13), transcript variant 6

RG217121 10 µg Ask for price

FGF13 (GFP-tagged) - Human fibroblast growth factor 13 (FGF13), transcript variant 1

RG204164 10 µg Ask for price

FGF13 (GFP-tagged) - Human fibroblast growth factor 13 (FGF13), transcript variant 4

RG227490 10 µg Ask for price

FGF13 (GFP-tagged) - Human fibroblast growth factor 13 (FGF13), transcript variant 2

RG227498 10 µg Ask for price

FGF13 (GFP-tagged) - Human fibroblast growth factor 13 (FGF13), transcript variant 3

RG227509 10 µg Ask for price

FGF13 (GFP-tagged) - Human fibroblast growth factor 13 (FGF13), transcript variant 5

RG227518 10 µg Ask for price

Fgf13 (Myc-DDK-tagged ORF) - Rat fibroblast growth factor 13 (Fgf13), (10 ug)

RR201615 10 µg Ask for price

Fgf13 ORF Vector (Rat) (pORF)

ORF067093 1.0 ug DNA
EUR 607.2

Fgf13 ORF Vector (Mouse) (pORF)

ORF044814 1.0 ug DNA
EUR 607.2

FGF13 ORF Vector (Human) (pORF)

ORF004034 1.0 ug DNA
EUR 114

Lenti ORF clone of Fgf13 (mGFP-tagged) - Mouse fibroblast growth factor 13 (Fgf13)

MR221854L4 10 µg Ask for price

FGF13 ELISA Kit (Rat) (OKCD00187)

OKCD00187 96 Wells
EUR 1075.2
Description: Description of target: Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (By similarity).By similarity May regulate voltage-gated sodium channels transport and function.By similarity May also play a role in MAPK signaling.By similarity ;Species reactivity: Rat;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 5.4 pg/mL

Human FGF13 knockout cell line

ABC-KH5509 1 vial Ask for price
Description: Human FGF13 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FGF13 knockdown cell line

ABC-KD5509 1 vial Ask for price
Description: Human FGF13 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human FGF13 Protein Lysate 20ug

IHUFGF13PLLY20UG each
EUR 213
Description: Human FGF13 Protein Lysate 20ug

FGF13 ELISA Kit (Human) (OKCD05284)

OKCD05284 96 Wells
EUR 1090.8
Description: Description of target: FGF13 is probably involved in nervous system development and function.The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located to a region associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a syndromal X-linked mental retardation, which suggests it may be a candidate gene for familial cases of the BFL syndrome. The function of this gene has not yet been determined. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.53pg/mL

Fgf13 ELISA Kit (Mouse) (OKCD01720)

OKCD01720 96 Wells
EUR 1028.4
Description: Description of target: Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Isoform 1 seems not to be involved in neuroblast polarization and migration but regulates axon branching. May regulate voltage-gated sodium channels transport and function. May also play a role in MAPK signaling. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 13.6 pg/mL

FGF13 (Myc-DDK-tagged)-Human fibroblast growth factor 13 (FGF13), transcript variant 4

RC227490 10 µg Ask for price

FGF13 (Myc-DDK-tagged)-Human fibroblast growth factor 13 (FGF13), transcript variant 2

RC227498 10 µg Ask for price

FGF13 (Myc-DDK-tagged)-Human fibroblast growth factor 13 (FGF13), transcript variant 3

RC227509 10 µg Ask for price

FGF13 (Myc-DDK-tagged)-Human fibroblast growth factor 13 (FGF13), transcript variant 5

RC227518 10 µg Ask for price

FGF13 (Myc-DDK-tagged)-Human fibroblast growth factor 13 (FGF13), transcript variant 1

RC204164 10 µg Ask for price

Fgf13 (myc-DDK-tagged) - Mouse fibroblast growth factor 13 (Fgf13), transcript variant 3

MR228408 10 µg Ask for price

Fgf13 (myc-DDK-tagged) - Mouse fibroblast growth factor 13 (Fgf13), transcript variant 2

MR228819 10 µg Ask for price

FGF13 (Myc-DDK-tagged)-Human fibroblast growth factor 13 (FGF13), transcript variant 6

RC217121 10 µg Ask for price

Genorise® recombinant Canine FGF13

GR122112 5 µg
EUR 285

OCOA13267-20UG - FGF13 Protein Lysate

OCOA13267-20UG 20ug
EUR 169

OCOA07053-20UG - FGF13 Protein Lysate

OCOA07053-20UG 20ug
EUR 169

FGF13 Over-expression Lysate Product

GWB-3A473B 0.1 mg Ask for price

ARP90557_P050 - Fgf13 Antibody Middle region

ARP90557_P050 100ul
EUR 389

FGF13 Polyclonal Antibody, HRP Conjugated

A59129
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  • Ask for price
  • 100 µg
  • 50 ul
  • 100 ul

Lenti ORF clone of Fgf13 (Myc-DDK-tagged) - Mouse fibroblast growth factor 13 (Fgf13)

MR221854L3 10 µg Ask for price

FGF13 Polyclonal Antibody, FITC Conjugated

A59128
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  • Ask for price
  • 100 µg
  • 50 ul
  • 100 ul

OPCA03132-1MG - FGF13 Recombinant Protein

OPCA03132-1MG 1mg
EUR 1379

OPCD03190-10UG - FGF13 Recombinant Protein

OPCD03190-10UG 10ug
EUR 159

OPCD03190-50UG - FGF13 Recombinant Protein

OPCD03190-50UG 50ug
EUR 389

OPCD03191-10UG - FGF13 Recombinant Protein

OPCD03191-10UG 10ug
EUR 179

OPCD03191-50UG - FGF13 Recombinant Protein

OPCD03191-50UG 50ug
EUR 429

OPCD03192-10UG - FGF13 Recombinant Protein

OPCD03192-10UG 10ug
EUR 139

OPCD03192-50UG - FGF13 Recombinant Protein

OPCD03192-50UG 50ug
EUR 349

OPCA03132-20UG - FGF13 Recombinant Protein

OPCA03132-20UG 20ug
EUR 218

FGF13 Polyclonal Antibody, Biotin Conjugated

A59127
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  • Ask for price
  • 100 µg
  • 50 ul
  • 100 ul

OPCD03190-200UG - FGF13 Recombinant Protein

OPCD03190-200UG 200ug
EUR 779

OPCD03191-200UG - FGF13 Recombinant Protein

OPCD03191-200UG 200ug
EUR 859

OPCD03192-200UG - FGF13 Recombinant Protein

OPCD03192-200UG 200ug
EUR 699

OPCA03132-100UG - FGF13 Recombinant Protein

OPCA03132-100UG 100ug
EUR 323

Nori® Rat FGF13 ELISA Kit

GR118113 96-well
EUR 461

Nori® Ovine FGF13 ELISA Kit

GR116102 96-well
EUR 461

Nori® Mouse FGF13 ELISA Kit

GR117120 96-well
EUR 461

Nori® Human FGF13 ELISA Kit

GR111234 96-well
EUR 461

Nori® Monkey FGF13 ELISA Kit

GR169115 96-well
EUR 461

Nori® Donkey FGF13 ELISA Kit

GR170115 96-well
EUR 461

Nori® Feline FGF13 ELISA Kit

GR188123 96-well
EUR 461

Nori® Canine FGF13 ELISA Kit

GR115199 96-well
EUR 461

Nori® Bovine FGF13 ELISA Kit

GR112147 96-well
EUR 461

Nori® Equine FGF13 ELISA Kit

GR106699 96-well
EUR 461

Nori® Rabbit FGF13 ELISA Kit

GR144104 96-well
EUR 461

Nori® Hamster FGF13 ELISA Kit

GR172123 96-well
EUR 461

Nori® Porcine FGF13 ELISA Kit

GR113169 96-well
EUR 461

OKCD00187-96W - FGF13 ELISA Kit (Rat)

OKCD00187-96W 96Wells
EUR 725

OKCD05284-96W - FGF13 ELISA Kit (Human)

OKCD05284-96W 96Wells
EUR 750

OKCD01720-96W - Fgf13 ELISA Kit (Mouse)

OKCD01720-96W 96Wells
EUR 700

Fgf13 sgRNA CRISPR Lentivector set (Rat)

K7114401 3 x 1.0 ug
EUR 406.8

Human Fibroblast growth factor 13 (FGF13)

1-CSB-EP008619HU
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Fibroblast growth factor 13(FGF13) expressed in E.coli

Lenti ORF clone of Fgf13 (mGFP-tagged ORF) - Rat fibroblast growth factor 13 (Fgf13), (10 ug)

RR201615L4 10 µg Ask for price

Active Fibroblast Growth Factor 13 (FGF13)

APC915Hu02 10ug
EUR 330

Active Fibroblast Growth Factor 13 (FGF13)

APC915Ra01 10ug
EUR 380

Active Fibroblast Growth Factor 13 (FGF13)

4-APC915Ra01
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  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Fibroblast Growth Factor 13 expressed in: E.coli

Fgf13 sgRNA CRISPR Lentivector set (Mouse)

K4392401 3 x 1.0 ug
EUR 406.8

Active Fibroblast Growth Factor 13 (FGF13)

RPU59224-100ug 100ug
EUR 1089

Active Fibroblast Growth Factor 13 (FGF13)

RPU59224-1mg 1mg
EUR 4826.3

Active Fibroblast Growth Factor 13 (FGF13)

RPU59224-50ug 50ug
EUR 726

Active Fibroblast Growth Factor 13 (FGF13)

RPU59275-100ug 100ug
EUR 1306.8

Active Fibroblast Growth Factor 13 (FGF13)

RPU59275-1mg 1mg
EUR 5791.5

Active Fibroblast Growth Factor 13 (FGF13)

RPU59275-50ug 50ug
EUR 871.2

Active Fibroblast Growth Factor 13 (FGF13)

RPU54958-100ug 100ug
EUR 1170.4

Active Fibroblast Growth Factor 13 (FGF13)

RPU54958-1mg 1mg
EUR 5187

Active Fibroblast Growth Factor 13 (FGF13)

RPU54958-50ug 50ug
EUR 940.5

FGF13 sgRNA CRISPR Lentivector set (Human)

K0778401 3 x 1.0 ug
EUR 406.8

Fibroblast Growth Factor 13 (FGF13) Antibody

20-abx322715
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  • 100 ul
  • 50 ul

Fibroblast Growth Factor 13 (FGF13) Antibody

20-abx318511
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Fibroblast Growth Factor 13 (FGF13) Antibody

20-abx327994
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  • 100 ug
  • 50 ug

Fibroblast Growth Factor 13 (FGF13) Antibody

20-abx320467
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  • 100 ul
  • 50 ul

Fibroblast Growth Factor 13 (FGF13) Antibody

abx330957-100ul 100 ul
EUR 510

Fibroblast Growth Factor 13 (FGF13) Antibody

20-abx176406
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Fibroblast Growth Factor 13 (FGF13) Antibody

20-abx176407
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  • 1 mg
  • 200 ug

Fibroblast Growth Factor 13 (FGF13) Antibody

20-abx176408
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  • 1 mg
  • 200 ug

Fibroblast Growth Factor 13 (FGF13) Antibody

20-abx176409
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug


Conclusion:
TGF-β3 effectively suppressed UVR-induced melanogenesis showed that topical TGF-β3 may be a suitable candidate for the treatment of hyperpigmentation, UV-related disorders.

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