Metabolic Messengers: fibroblast growth factor 15/19

Metabolic Messengers: fibroblast growth factor 15/19

Fibrocoblast growth factor (FGF) 15 in the mouse and its human orthologist FGF19 (set rated FGF15 / 19) are intestinal hormones that control the homeostasis of bile acids and glucose during the transition from the Fed to the Gamening state. In addition to its central role in the regulation of the biliary homeostasis, FGF15 / 19 is now recognized as a cross-cutting metabolic coordinator at the crossroads of the gut, liver, brain and adipose white tissue. The dysregulation of the signaling FGF15 / 19 can contribute to the pathogenesis of several diseases affecting the axis of the gut liver and metabolic diseases.

Here we provide an overview of the current knowledge of the physiological roles of the entockin FGF15 / 19 and to highlight the commonalities and differences between the two orthologists. We also discuss the putative therapeutic potential in areas of unmet medical needs – such as cholesatic liver diseases and non-alcoholic steatohepatitis, for which FGF19 is tested in current clinical trials, as well as the possibility of using the FGF19 for the treatment of obesity and type II diabetes. Two patients have developed a trichiasis and a dry eye after FGFR inhibitor therapy. The treatments included artificial tears, life for life or cyclosporin and hair removal. A patient has stopped treatment with AZD4547 due to the severity of ocular adverse effects.

Neurotrophic factors have been considered promising potential for neuronal protection and regeneration and thus promote beneficial effects of kinesiological functions. They can be suspected of playing important roles in cellular transplant / fabric for various neuronal diseases. Clinical applications of such trophic factors to the central nervous system (CNS), however, caused problematic side effects due to distinctive bioactive properties. During the development of synthetic compounds reflecting the beneficial properties of the basic fibroblast growth factor (BFGF), we conducted filter candidates that stimulate to trigger the phosphorylation of intracellular tyrosine of the FGF receiver and leads to intracellular signaling. later in neurons.

The 4-Level Tumor Growth Factor Receiver provides for the effectiveness of lenvatinib in patients with advanced hepatocellular carcinoma

Objectives: Biomarkers optimizing the results of the treatment with lenvatinib in patients with advanced hepatocellular carcinoma remain to be put in place despite intense and global genomic research. Lenvatinib is characterized by its important inhibitory power for the fibroblast growth factor receiver (FGFR) 4 compared to earlier tyrosine kinase inhibitors. Thus, in this study, we focused on a simplified quantization of the FGFR4 in tumors as a potential predictive indicator.

Methods: According to cancer genome Atlas Data data set, the FGFR4 messenger RNA is largely overexpressed in hepatocellular carcinoma in the absence of genes alteration. The analysis of genes enrichment revealed that the aggressiveness of the tumor was closely linked to the FGFR4 level. To confirm the relationship between the benefits of lenvatinib and the tumor dependence along the FGFR4 way, we analyzed protein levels in tumors and peripheral blood obtained from 57 patients registered prospectively treated with lenvatinib.

Results: Positive immunohistochemistry (> 10% of tumor cells) For the FGFR4 in the biopsy samples before treatment is associated with a longer progression survival (2.5 vs 5.5 months, p = 0.01) and a favorable objective response rate (31% against 81%, p = 0.006). On the other hand, the concentration of FGFR4 soluble in the peripheral blood, measured by an immunosorbent dosage related to an enzyme, has not been associated with survival results because its fluctuations reflect hepatic fibrosis. An additional analysis of RNA sequencing using archival surgical samples (n = 90) suggested that FGFR4’s alternative RNA splicing in cancer may also explain this divergence.

 Metabolic Messengers: fibroblast growth factor 15/19
Metabolic Messengers: fibroblast growth factor 15/19

YAP improves the proliferation of neuronal stem cells dependent on the FGF2 by induction of fibroblast growth factor receptor expression

The signaling path of the hippopotage regulates cell proliferation and organ growth and its activation is mainly reflected by YAP phosphorylation levels. We show here that YAP facilitates the proliferation of embryonic neural stem cells by raising their reactivity to the growth factor of Fibroblast 2 (FGF2), one of the main growth factors of neural stem cells, in vivo and in vitro. Western real-time and quantitative PCR analyzes revealed that FGFR1 FGFR4 receptors in FGFR4 has been significantly increased by YAP expression during FGF2 treatment, followed by increased marketing signal marketing. MAPK and AKT.

In addition, as evaluated by quantitative real-time PCR analyzes, YAP-induced FGFRS expression was deemed independent of Tead, and Taz, the other Yorki counterpart in the Drosophila Hippo signaling path, was noted possess an activity similar to YAP. Finally, the setting of the FGFR signaling activity in expressing YAP cells to effectively control the proliferative effects of YAP cell, suggesting that the increased proliferation of YAP express neural stem cells was mainly attributable to improved FGFR signaling. Our data indicates that YAP plays an important role in the regulation of neuronal stem cells by increasing the expression of the FGFR, then resulting in increased cell proliferation.

Human Tonsil Fibroblasts

ABC-TC3835 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. There is good evidence that fibroblasts in different parts of the body are intrinsically different. Fibroblasts within tissues are exposed to a dynamic mechnical environment, which influences the structure integrity of both healthy and healing soft tissue. Fibroblasts secrete a nonrigid extracellular matrix that is rich in type I and/or type III collagen They are responsible for much of the synthesis of extracellular matrix in connective tissues and play major roles in wound healing. Many diseases are associated with fibroblasts, either because fibroblasts are implicated in their etiology or because of the fibrosis that accompanies damage to other cell types in tissues. Fibroblasts are among the most accessible normal mammalian cell types and still the most amenable to culture in vitro.HTF from Gentaur Research Laboratories are isolated from human tonsils. HTF are cryopreserved at passage one and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HTF are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HTF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HTF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Kidney Fibroblasts

ABC-TC5519 1 vial Ask for price
Description: Human Kidney Fibroblasts are isolated from the human adult healthy renal tissue. HKF-a are cryopreserved after passage one culture and delivered frozen. HKF-a are guaranteed to further expand for 15 population doublings under the conditions provided by in the technical sheet.As an excretory organ in the urinary system, the kidney greatly influences an individual’s well being by preserving homeostasis through regulating electrolytes, pH, and blood pressure among other control mechanisms. Comprising the majority of interstitial cells in the kidney, renal fibroblasts are responsible for the synthesis of collagen I of the extracellular matrix. Also, renal cortical fibroblasts synthesize erythropoietin, an important glycoprotein hormone that controls the production of red blood cells and renal medullary fibroblasts produce prostaglandins, a class of autocrine or paracrine hormones, which help maintain water and electrolyte homeostasis. Renal interstitial fibrosis, a disorder that may escalate to chronic kidney disease, is often correlated with excessive deposition of extracellular matrix by renal fibroblasts, the regulation of which process is under intensive research.

Native Human Fibroblasts

SC00A5 500,000 Cells
EUR 1086

Human Kidney Fibroblasts

CSC-8240W One Frozen vial Ask for price

Human Dermal Fibroblasts

CSC-C0519Z One Frozen vial Ask for price

Human Spleen Fibroblasts

CSC-C4868L One Frozen vial Ask for price

Human Adrenal Fibroblasts

ABC-TC3478 1 vial Ask for price
Description: The adrenal gland plays an essential role in regulating homeostasis in the body through the secretion of corticosteroid and androgen hormones. Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. Fibroblasts secrete a non-rigid extracellular matrix that is rich in type I and/or type III collagen. They are responsible for much of the synthesis of extracellular matrix in connective tissues and play major roles in wound healing. Many diseases are associated with fibroblasts, either because fibroblasts are implicated in their etiology or because of the fibrosis that accompanies damage to other cell types in tissues. For example, the development of bowl stenosis in Crohn’s disease patients is caused by extreme fibroblast proliferation and extracellular matrix expansion.HAdF from Gentaur Research Laboratories are isolated from human adrenal tissue. HAdF are cryopreserved at passage one and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HAdF are characterized by their spindle morphology and immunofluorescence with antibody specific to fibronectin. HAdF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HAdF are guaranteed to further expand for 15 population doublings under the conditions provided by Gentaur Research Laboratories.

Human Cardiac Fibroblasts

ABC-TC3533 1 vial Ask for price
Description: The cardiac fibroblasts (CF) are the principal cell type of the heart. They provide structural support for cardiac myocytes and are responsible for extracellular matrix synthesis in the heart during growth and pathophysiological conditions. CF are an important cellular component of myocardial responses to injury and the source of paracrine growth factors. Their proliferation and synthesis of matrix is essential for scar formation at sites of myocardial infarction, cardiac fibrosis, and is often complicated by cardiac hypertrophy. CF also respond to changing environments in pathophysiological conditions by modulating integrin expression. CF culture has been widely used as a model to study the cardiac matrix remodeled by physiological (exercise) and pathological (hypertension) stressors.HCF from Gentaur Research Laboratories are isolated from the human heart. HCF-a are cryopreserved at secondary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HCF-a are characterized by immunofluorescent method with antibody to fibronectin. HCF-a are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HCF-a are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Mammary Fibroblasts

ABC-TC3694 1 vial Ask for price
Description: Fibroblasts are the most common types of mammary stromal cells. Mammary stromal cells differentiate into fibroblasts, adipocytes or vascular structures in a hormone- and substatum-dependent manner, and may explain the dramatic changes in stromal composition during both normal mammary gland development and tumorigenesis. The interaction between stromal cells and tumor cells is known to play a major role in cancer growth and progression. The Mammary stromal fibroblasts express and produce cytokines such as SF witch plays roles in mammary cancer. HMF from Gentaur Research Laboratories are isolated from human mammary tissue. HMF are cryopreserved at primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HMF are characterized by immunofluorescent method with antibodies to fibronectin, CD90 and vimentin. HMF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HMF are guaranteed to further expand for 15 population doublings at the conditions provided by Gentaur Research Laboratories.

Human Ovarian Fibroblasts

ABC-TC3741 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. There is good evidence that fibroblasts in different parts of the body are intrinsically different. Fibroblasts within tissues are exposed to a dynamic mechnical environment, which influences the structure integrity of both healthy and healing soft tissue. Fibroblasts secrete a nonrigid extracellular matrix that is rich in type I and/or type III collagen. Ovarian fibroblasts stimulate human ovarian cancer cell invasion and expression of 72-kDa gelatinase A (MMP-2).HOF from Gentaur Research Laboratories are isolated from human ovary tissue. HOF are cryopreserved at primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HOF are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HOF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HOF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Splenic Fibroblasts

ABC-TC3818 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. Fibroblasts within tissues are exposed to a dynamic mechnical environment, which influences the structure integrity of both healthy and healing soft tissue. They secrete a non-rigid extracellular matrix that is rich in type I and/or type III collagen. There is good evidence that fibroblasts in different parts of the body are intrinsically different and display different regulatory functions on surrounding cells. For example, splenic fibroblasts have been shown to regulate the development of NK cells from blood progenitors through an expression of bioactive IL-15. HSF from Gentaur Research Laboratories are isolated from human spleen tissue. HSF are cryopreserved at primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HSF are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HSF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HSF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Thyroid Fibroblasts

ABC-TC3832 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. There is good evidence that fibroblasts in different parts of the body are intrinsically different. Fibroblasts secrete a non-rigid extracellular matrix that is rich in type I and/or type III collagen. They are responsible for much of the synthesis of extracellular matrix in connective tissues and play major roles in wound healing. Many diseases are associated with fibroblasts, either because fibroblasts are implicated in their etiology or because of the fibrosis that accompanies damage to other cell types in tissues. Because the thyroid is easily susceptible to inflammatory autoimmune diseases that can result in tissue damage, thyroid fibroblasts may play an important role in regulating thyroid function and reaction to disease. HThF from Gentaur Research Laboratories are isolated from human thyroid tissue. HThF are cryopreserved at passage one and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HThF are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HThF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HThF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Uterine Fibroblasts

ABC-TC3863 1 vial Ask for price
Description: Derived from the mesoderm, connective tissue is involved in maintaining the structural integrity of the body. The predominant cells found in connective tissue are fibroblasts, which continuously secrete various components of the extracellular matrix. Depending on the site of origin and physiological status, fibroblasts may exhibit different morphological phenotypes and various functional properties.Gentaur offers a range of Human Fibroblasts produced at Gentaur's cell culture facility. The cells are isolated from normal human juvenile foreskin or adult skin from different locations. In addition, Gentaur offers Fibroblasts from adult lung tissue, aortic adventitial tissue, and villous placental tissue.Shortly after isolation, all Gentaur Human Fibroblasts are cryopreserved at passage 2 (P2) using Gentaur's proprietary, serum-free freezing medium,Cryo-SFM. Each cryo vial contains more than 500,000 viable cells after thawing. Proliferating cell cultures are made from 500,000 cryopreserved cells that have been thawed and cultured for three days at Gentaur.

Human Gastric Fibroblasts

ABC-TC5516 1 vial Ask for price
Description: Gastric fibroblasts (GF), which are located in the stomach, are mesenchymal cells derived from the embryonic mesoderm. Fibroblasts secrete a non-rigid extracellular matrix that is both rich in type I and/or type III collagen. They are responsible for much of the synthesis of extracellular matrix in connective tissues and play a central role in wound healing. Studies in vitro and in vivo show that GF can regulate epithelial regeneration by influencing epithelial cell proliferation and differentiation. In addition to their role in wound healing, human GF (HGF) have been shown to be key contributors in the development and progression of gastric carcinoma. HGF are a useful model for examining the underlying mechanisms that cause gastric carcinoma and may provide novel insights for developing new cancer drug therapies.

Human Thyroid Fibroblasts 

CSC-7702W One Frozen vial Ask for price

Human Colonic Fibroblasts

CSC-8242W One Frozen vial Ask for price

Human Hepatic Fibroblasts

CSC-C1500 One Frozen vial Ask for price

Human Cardiac Fibroblasts

CSC-C1503 One Frozen vial Ask for price

Human Mammary Fibroblasts

CSC-C1527 One Frozen vial Ask for price

Human Splenic Fibroblasts 

CSC-C9230J One Frozen vial Ask for price

Human Gingival Fibroblasts

ABC-TC3627 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells with many vital functions during development and in adult organisms. They are responsible for much of the synthesis of extracellular matrix in connective tissues and play major roles in wound healing. Many diseases are associated with fibroblasts, either because fibroblasts are implicated in their etiology or because of the fibrosis that accompanies damage to other cell types in tissues. Fibroblasts are among the most accessible normal mammalian cell types and still the most amenable to culture in vitro. Gingival fibroblasts are the major constituents of gingival tissue and play a key role in their health maintenance. Human gingival fibroblasts (HGnF) express a wide surface molecular panel including mainly CD9, CD26, CD55, CD59, CD63, CD71, CD86 CD95, CD99 and CD117. They were also demonstrated to express mRNAs for protease-activated receptor-1 (PAR-1) and PAR-3.HGnF from Gentaur Research Laboratories are isolated from human gingiva. HGnF are cryopreserved at passage one and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HGnF are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HGnF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HGnF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Prostate Fibroblasts

ABC-TC3765 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of the easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. There is good evidence that fibroblasts in different parts of the body are intrinsically different. Fibroblasts within tissues are exposed to a dynamic mechnical environment, which influences the structure integrity of both healthy and healing soft tissue. Fibroblasts secrete a nonrigid extracellular matrix that is rich in type I and/or type III collagen. Cultured prostate fibroblasts synthesize FGF-like growth factor that stimulate their growth and is believed to be important in the development of benign prostatic hyperplasia.HPrF from Gentaur Research Laboratories are isolated from human prostate tissue. HPrF are cryopreserved at primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HPrF are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HPrF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HPrF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human pancreas fibroblasts

P0018025 One Frozen vial
EUR 580

Human Prostate Fibroblasts 

CSC-7730W One Frozen vial Ask for price

Human Gingival Fibroblasts

cAP-0140 1Frozen Vial
EUR 693

Human Prostate Fibroblasts

ALHE28 1ml frozen Vial
EUR 620

Human Bronchial Fibroblasts

ABC-TC3529 1 vial Ask for price
Description: Human Bronchial Fibroblasts from Gentaur Research Laboratories are isolated from human bronchus tissue. HBF are cryopreserved at secondary culture (P1) and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HBF are characterized by immunofluorescent method with antibody to fibronectin. HBF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HBF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Lymphatic Fibroblasts

ABC-TC3688 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. There is good evidence that fibroblasts in different parts of the body are intrinsically different. Fibroblasts within tissues are exposed to a dynamic mechnical environment, which influences the structure integrity of both healthy and healing soft tissue. Fibroblasts secrete a nonrigid extracellular matrix that is rich in type I and/or type III collagen. Besides, dermal fibroblasts also secrete large quantities of hyaluronan in response to inflammatory stimuli. During wound healing, dermal fibroblasts switch from a migratory, repopulating phenotype to a contractile, matrix-reassembling phenotype.HLF from Gentaur Research Laboratories are isolated from human lymph nodes. HLF are cryopreserved at primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HLF are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HLF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HLF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Pulmonary Fibroblasts

ABC-TC3776 1 vial Ask for price
Description: The most abundant cell type in lung interstitium is fibroblasts. They resemble ordinary fibroblasts but have some distinguishing features, for example, they have long branching processes and gap junctions. Their principle function is production of type III collagen, elastin, and proteoglycans of the extracellular matrix of the alveolar septa. Pulmonary fibroblasts (PF) play an important role in the repair and remodeling processes following injury. The controlled accumulation of fibroblasts to sites of inflammation is crucial to effective tissue repair after injury. Either inadequate or excessive accumulation of fibroblasts could result in abnormal tissue function. For example, the excess proliferation of fibroblasts contributes to the adventitial thickening observed during the development of hypoxia-induced pulmonary hypertension. HPF from Gentaur Research Laboratories are isolated from human lung tissue. HPF are cryopreserved at primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HPF are characterized by immunofluorescent method with antibody to fibronectin. HPF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HPF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Intestine Fibroblasts

cAP-0206 1Frozen Vial
EUR 544.5

Human Esophageal Fibroblasts

ABC-TC3613 1 vial Ask for price
Description: Esophageal fibroblasts which line the lamina propria of the upper and lower esophagus are mesenchymal cells that originated from the embryonic mesoderm. They have been shown to play an important role in angiogenesis through TGF-β and VEGF signaling pathways in the highly angiogenic esophageal squamous cell carcinoma. Predominantly, fibroblasts secrete a nonrigid extracellular matrix that is both rich in type I and/or type III collagen. They are responsible for much of the synthesis of extracellular matrix in the connective tissues and play major roles in wound healing. Because they are one of the simplest types of cells to grow in culture fibroblasts have been extensively used for a wide range of cellular and molecular studies. In addition, fibroblasts’ durability makes them amenable to a wide variety of manipulations ranging from gene transfection to microinjection.The HEF cells from Gentaur Research Laboratories are isolated from human esophageal tissue. HEF are cryopreserved at passage one and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HEF are characterized by immunofluorescence with antibody specific to fibronectin. HEF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HEF are guaranteed to further expand for 15 population doublings at the conditions provided by Gentaur Research Laboratories.

Human Intestinal Fibroblasts

ABC-TC3655 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. There is good evidence that fibroblasts in different parts of the body are intrinsically different. Fibroblasts secrete a non-rigid extracellular matrix that is rich in type I and/or type III collagen. They are responsible for much of the synthesis of extracellular matrix in connective tissues and play major roles in wound healing. Many diseases are associated with fibroblasts, either because fibroblasts are implicated in their etiology or because of the fibrosis that accompanies damage to other cell types in tissues. For example, the development of bowl stenosis in Crohn’s disease patients is caused by extreme fibroblast proliferation and extracellular matrix expansion.HIF from Gentaur Research Laboratories are isolated from human intestinal tissue. HIF are cryopreserved at passage one and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HIF are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HIF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HIF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Pancreatic Fibroblasts

ABC-TC5470 1 vial Ask for price
Description: Human Primary Pancreatic Fibroblasts are isolated from normal human pancreatic tissue. Human Primary Pancreatic Fibroblasts are grown in T75 tissue culture flasks pre-coated with gelatin-based coating solution for 2 min and incubated in Gentaur's Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells at passage 1 are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 0.5x106 cells per ml.

Human Pancreatic Fibroblasts

CSC-C4882L One Frozen vial Ask for price

Human Pancreatic Fibroblasts

cAP-0144 1Frozen Vial
EUR 693

Human Gallbladder Fibroblasts

ABC-TC3625 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. Because they are one of the easiest types of cells to grow in culture, they have been extensively used for a wide range of cellular and molecular studies. Additionally, their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. Fibroblasts secrete a non-rigid extracellular matrix that is rich in type I and/or type III collagen. They are responsible for much of the synthesis of extracellular matrix in connective tissues and play major roles in wound healing. Human gallbladder fibroblasts (HGBF) are responsible for eicosanoid synthesis, specifically PGI2. Chronic stimulation of HGBF results in up-regulated synthesis and release of PGI2 which aids in formation of early acute cholecystitis. HGBF are very versatile cells and could be used in studies of many conditions, such as the early stages of acute cholecystitis.HGBF from Gentaur Research Laboratories are isolated from human gallbladder tissue. HGBF are cryopreserved at passage one and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HGBF are characterized by their spindle morphology and immunofluorescence with antibody specific to fibronectin. HGBF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HGBF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Pericardial Fibroblasts

ABC-TC3748 1 vial Ask for price
Description: Pericardial Fibroblasts are the principal cell type of the serous pericardium. They help to form the strong connective tissue that allows the pericardium to serve as a protective sac for the heart. Pericardial fibroblasts are exposed to a dynamic mechanical environment, being attached to the diaphragm, which influences the structure integrity of both healthy and healing tissue. Fibroblasts secrete a non-rigid extracellular matrix that is rich in type I and/or type III collagen and there is good evidence that fibroblasts in different parts of the body are intrinsically different. Fibroblasts have been extensively used for a wide range of cellular and molecular studies because they are one of easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection.HPcF from Gentaur Research Laboratories are isolated from the human heart. HPcF are cryopreserved at secondary culture (passage one) and are delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HPcF are characterized by immunofluorescent method with antibody to fibronectin. HPcF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HPcF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Parathyroid Fibroblasts

cAP-0218 each
EUR 782.1

TIMP-2, human fibroblasts

7788-5 each
EUR 405.6

Human Conjunctival Fibroblasts

ABC-TC3574 1 vial Ask for price
Description: The fibroblast is the cellular element responsible for fibrosis. Conjunctival fibroblasts, as other fibroblasts, act not only as structural cells in the production of the matrix components, but are also actively involved as effectors in allergic conjunctivitis. Conjunctival fibroblasts cultured with histamine induce the production of proinflammatory cytokines, such as IL-1, IL-6 and IL-8. Conjunctival fibroblast culture can serve as a useful in vitro model for rapid screening of drugs for their effect on fibroblast morphology, motility, and proliferation, and provide a basis for the development of new treatments for a variety of ocular proliferative disorders.HConF from Gentaur Research Laboratories are isolated from human conjunctiva. HConF are cryopreserved at primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HConF are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HConF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HConF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Immortalized Human Fibroblasts

ABI-TC052D 1 vial Ask for price
Description: Fibroblasts are the most common cells of mammalian connective tissue. Gentaur offers an Immortalised fibroblast cell line originated from the human foreskin.

Human Lung Fibroblasts, Adult

ABC-TC3683 1 vial Ask for price
Description: Human Lung Fibroblasts (HLF) are derived from normal human lung parenchyma. They are cryopreserved at first passage and can be cultured and propagated at least 12 population doublings.

Human Skin Cells (Fibroblasts)

ABC-TC3807 1 vial Ask for price
Description: Human fibroblasts are derived from cultured skin explants. These fibroblasts are from a single donor.

Human Lung Fibroblasts, Foetal

ABC-TC3684 1 vial Ask for price
Description: Human Lung Fibroblasts (HLF) are derived from normal human lung parenchyma. They are cryopreserved at first passage and can be cultured and propagated at least 12 population doublings.

Human Dermal Fibroblasts (HDFa)

P0020022 One Frozen vial
EUR 420

Human Dermal Fibroblasts, Fetal

ABC-TC3588 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. There is good evidence that fibroblasts in different parts of the body are intrinsically different. Fibroblasts within tissues are exposed to a dynamic mechnical environment, which influences the structure integrity of both healthy and healing soft tissue. Fibroblasts secrete a nonrigid extracellular matrix that is rich in type I and/or type III collagen. In addition, dermal fibroblasts also secrete large quantities of hyaluronan in response to inflammatory stimuli. During wound healing, dermal fibroblasts switch from a migratory, repopulating phenotype to a contractile, matrix-reassembling phenotype.HDF from Gentaur Research Laboratories are isolated from fetal human skin. HDF are cryopreserved at primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HDF are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HDF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HDF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Vas Deferens Fibroblasts

ABC-TC3867 1 vial Ask for price
Description: Special edition cells are isolated from the tissue types described. Cells are sterility and virus tested. All tissues used for cell isolation are obtained under informed consent. Gentaur complies with the U.S. Health Insurance Portability and Accountability Act (HIPAA). Characterization standards for special edition cells have not been established.

Human Dermal Fibroblasts, Adult

ABC-TC3029 1 vial Ask for price
Description: Human Dermal Fibroblasts-Adult are isolated from adult human skin. Human Dermal Fibroblasts-Adult are cryopreserved at P0 and delivered frozen. Human Dermal Fibroblasts-Adult are characterized by their spindle morphology and immunofluorescence with antibody specific to fibronectin. Human Dermal Fibroblasts-Adult are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi.Human Dermal Fibroblasts provide an ideal cell system to establish serum free human feeder layers for human embryonic stem cell cultures or as a model to study wound healing, toxicology or basic cell biology. Fibroblasts are cryopreserved as primary cells to ensure the highest viability and plating efficiency.

Human Dermal Fibroblasts (Adult)

cAP-0008-ad 1Frozen Vial
EUR 445.5

Human Dermal Fibroblasts, Pooled

ABC-TC3399 1 vial Ask for price
Description: For routine cell cultivation, We recommends to work without antibiotics / antimycotics. For isolation, However, we recommend the use of antibiotics / antimycotics up to passage 2.

Human Lung Fibroblasts-Adults

cAP-0033Ad 1Frozen Vial
EUR 594

Human Choroid Plexus Fibroblasts

ABC-TC3569 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells, which they derived from the embryonic mesoderm. Although cells loosely called fibroblasts have been isolated from many tissues and assumed to be connective tissue cells, fibroblasts appear to be the least specialized cells. There is good evidence that fibroblasts in different parts of the body are intrinsically different. Fibroblasts secrete a nonrigid extracellular matrix that is rich in type I and/or type III collagen. Fibroblasts are the easiest of cells to grow in culture-a feature that has made them a favorite subject for cell biological studies.HCPF from Gentaur Research Laboratories are isolated from human choroid pluxus. HCPF are cryopreserved at primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HCPF are characterized by immunofluorescent method with antibody to fibronectin. HCPF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HCPF are guaranteed to further expand for 15 population doublings in the condition provided by Gentaur Research Laboratories.

Human Lymphatic Fibroblasts Cell

ABC-TC3689 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies.

Human Ocular Choroid Fibroblasts

ABC-TC3729 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They are one of the easiest types of cells to grow in culture and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. Fibroblasts secrete a non-rigid extracellular matrix that is rich in type I and/or type III collagen. During wound healing, fibroblasts switch from a migrator, repopulation phenotype to a contractile, matrix-reassembling phenotype. Choroid fibroblasts are exposed to a dynamic environment that influences cellular VEGF expression, which plays a significant role in angiogenesis and macular degeneration.HOCF from Gentaur Research Laboratories are isolated from human ocular choroid tissue. HOCF are cryopreserved at primary culture. Each vial contains 5×10^5 cells in 1 ml volume. HOCF are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HOCF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HOCF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Dermal Fibroblasts-fetal 

CSC-7797W One Frozen vial Ask for price

Human Dermal Fibroblasts, Neonatal

ABC-TC3451 1 vial Ask for price
Description: Human Dermal Fibroblasts-Neonatal are isolated form neonatal human skin. Human Dermal Fibroblasts-Neonatal are cryopreserved at P1 and delivered frozen. Human Dermal Fibroblasts-Neonatal are characterized by their spindle morphology and immunofluorescence with antibody specific to fibronectin. Human Dermal Fibroblasts-Neonatal are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi.

Human Bladder Stromal Fibroblasts

ABC-TC3515 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of the easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. There is good evidence that fibroblasts in different parts of the body are intrinsically different. Fibroblasts within tissues are exposed to a dynamic mechanical environment, which influences the structure integrity of both healthy and healing soft tissue. Fibroblasts secrete a nonrigid extracellular matrix that is rich in type I and/or type III collagen. As cells of mesenchymal origin, human bladder stromal fibroblasts (HBdSF) also secrete FGF-7, which interact primarily with bladder epithelial cells. FGF-7 secreted by HBdSF is essential for stimulating the formation of a multilayered stratified bladder epithelium. HBdSF from Gentaur Research Laboratories are isolated from human bladder tissue. HBdSF are cryopreserved at secondary culture (passage one) and are delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HBdSF are characterized by immunofluorescent method with antibody to fibronectin. HBdSF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HBdSF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Primary Uterine Fibroblasts

T4084 5x10^5 cells / 1.0 ml Ask for price

Human Primary Cardiac Fibroblasts

T4038 5x10^5 cells / 1.0 ml
EUR 1375

Gaucher Disease Human Fibroblasts

T4135 1x10^6 cells / 1.0 ml Ask for price

Human Dermal Fibroblasts (Neonatal)

cAP-0008-neo 1Frozen Vial
EUR 445.5

Human Cardiac Fibroblasts-Atrial

ABC-TC3537 1 vial Ask for price
Description: Human Cardiac-Related Fibroblasts include Aortic Adventitial Fibroblasts (AoAF) isolated from the tunica external of the ascending or descending aorta and cardiac fibroblasts (NHCF-A and -V) isolated from the atrium or verticle.

Human Fibroblasts-GFP Expressing

GFP07 500,000 Cells in T25 flask
EUR 1624.8

Human Primary Tracheal Fibroblasts

T4005 5x10^5 cells / 1.0 ml Ask for price

Human Primary Neonatal Fibroblasts

T4104 5x10^5 cells / 1.0 ml Ask for price

Human Aortic Adventitia Fibroblasts

ABC-TC3490 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells which derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. There is good evidence that fibroblasts in different parts of the body are intrinsically different. The pulmonary arterial vesculature responds to various insults with a characteristic pattern of remodeling that includes an increase in connective tissue in the medial layer of the vessel wall. One of the pathogenetic mechanisms involved is the functional derangements of vascular fibroblasts. Their proliferative response contributes to the adventitial thickening observed during the development of hypoxia-induced hypertension. HAAF from Gentaur Research Laboratories are isolated from human aortic artery. HAAF are cryopreserved at first passage of primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HAAF are characterized by spindle morphology and by immunofluorescent method with antibody to fibronectin. HAAF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HAAF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Bladder Fibroblasts, Secondary

ABC-TC3512 1 vial Ask for price
Description: Special edition cells are isolated from the tissue types described. Cells are sterility and virus tested. All tissues used for cell isolation are obtained under informed consent. Gentaur complies with the U.S. Health Insurance Portability and Accountability Act (HIPAA). Characterization standards for special edition cells have not been established.

Human Primary Pulmonary Fibroblasts

T4009 5x10^5 cells / 1.0 ml
EUR 975

Human Primary Epidermal Fibroblasts

T0300 5x10^5 cells / 1.0 ml
EUR 625

Human Aortic Adventitial Fibroblasts

ABC-TC3033 1 vial Ask for price
Description: Human Cardiac-Related Fibroblasts include Aortic Adventitial Fibroblasts (AoAF) isolated from the tunica external of the ascending or descending aorta and cardiac fibroblasts (NHCF-A and -V) isolated from the atrium or verticle.

Human Primary Esophageal Fibroblasts

T4232 5x10^5 cells / 1.0 ml Ask for price

Human Peridontal Ligament Fibroblasts

ABC-TC3750 1 vial Ask for price
Description: The periodontal ligament is a connective tissue located between the cementum of teeth and the alveolar bone of the mandibula. It plays an integral role in the maintenance and regeneration of periodontal tissue. The cells responsible for maintaining this tissue are thought to be fibroblasts, which can be either multipotent or composed of heterogenous cell populations that differ in their function. Despite the similar morphology with gingival fibroblasts, periodontal ligament fibroblasts (PDLF) appear to display distinct functional activities in the maintenance of tissue integrity. It is known that PDLF produce osteoblast-related extracellular matrix proteins and show higher alkaline phosphatase activity compared with gingival fibroblasts. PDLF actively participate in immune and inflammatory events in periodontal diseases.HPDLF from Gentaur Research Laboratories are isolated from human periodontal tissue. HPDLF are cryopreserved at passage one and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HPDLF are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HPDLF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HPDLF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Villous Mesenchymal Fibroblasts

ABC-TC3869 1 vial Ask for price
Description: Derived from the mesoderm, connective tissue is involved in maintaining the structural integrity of the body. The predominant cells found in connective tissue are fibroblasts, which continuously secrete various components of the extracellular matrix. Depending on the site of origin and physiological status, fibroblasts may exhibit different morphological phenotypes and various functional properties.Gentaur offers a range of Human Fibroblasts produced at Gentaur's cell culture facility. The cells are isolated from normal human juvenile foreskin or adult skin from different locations. In addition, Gentaur offers Fibroblasts from adult lung tissue, aortic adventitial tissue, and villous placental tissue.Shortly after isolation, all Gentaur Human Fibroblasts are cryopreserved at passage 2 (P2) using Gentaur's proprietary, serum-free freezing medium,Cryo-SFM. Each cryo vial contains more than 500,000 viable cells after thawing. Proliferating cell cultures are made from 500,000 cryopreserved cells that have been thawed and cultured for three days at Gentaur.

Immortalized Human Uterine Fibroblasts

T0610 1x106 cells / 1.0 ml
EUR 2750

Immortalized Human Cardiac Fibroblasts

T0446 1x106 cells / 1.0 ml
EUR 3950

Human Periodontal Ligament Fibroblasts

CSC-C4607J One Frozen vial Ask for price

Immortalized Human Cardiac Fibroblasts

CSC-I9134L One Frozen vial Ask for price

Human Skin Cells (Fibroblasts, Prenata)

ABC-TC3809 1 vial Ask for price
Description: Human fibroblasts are derived from cultured skin explants. Human fibroblasts are from a single donor. These cells enable researchers to study skin diseases such as dermatitis, wound healing, and other diseases that are expressed in fibroblast. In addition, they may be used to study the development of skin and production of inducible pluripotent stem cells. Development period: Prenata

Human MMC treated Dermal Fibroblasts

ABC-TC3983 1 vial Ask for price
Description: MCFibs provide an ideal cell system to establish human feeder layers for the culture of embryonic stem cells or other cell types requiring a feeder layer for optimal proliferation. MCFibs are quality tested in LIFib's Serum-Free Medium to ensure high viability and plating efficiency. Cell Features:MCFibs are cryopreserved after secondary culture and treatment with MMC.MCFibs remain viable and attached in serum-free, animal protein-free, phenol red-free, and antimicrobial-free medium.MCFibs are extensively tested for quality and optimal performance.MCFibs are ready to use.MCFibs are pretreated to help reduce toxic agents in your lab.Gentaur guarantees performance and quality.MCFibs are tested for suitability as feeder layers for human embryonic stem cell cultures.

Human Cardiac Fibroblasts-Ventricular

ABC-TC3539 1 vial Ask for price
Description: Human Cardiac-Related Fibroblasts include Aortic Adventitial Fibroblasts (AoAF) isolated from the tunica external of the ascending or descending aorta and cardiac fibroblasts (NHCF-A and -V) isolated from the atrium or verticle.

Immortalized Human Foreskin Fibroblasts

CSC-I2034Z One Frozen vial Ask for price

Complete Medium For Human Fibroblasts

HXXFB-90011 500mL
EUR 250

Human Skin Cells (Fibroblasts, Postnatal)

ABC-TC3808 1 vial Ask for price
Description: Human fibroblasts are derived from cultured skin explants. Human fibroblasts are from a single donor. These cells enable researchers to study skin diseases such as dermatitis, wound healing, and other diseases that are expressed in fibroblast. In addition, they may be used to study the development of skin and production of inducible pluripotent stem cells. Development period: Postnatal

FIBROBLASTS, Antibody

GWB-4390F9 0.1 mg Ask for price

Fibroblasts Antibody

GWB-833798 0.1 mg Ask for price

Human Cardiac Fibroblasts-Adult Atrial

ABC-TC3535 1 vial Ask for price
Description: The cardiac fibroblasts (CF) are the principal cell type of the heart. They provide structural support for cardiac myocytes and are responsible for extracellular matrix synthesis in the heart during growth and pathophysiological conditions. CF are an important cellular component of myocardial responses to injury and the source of paracrine growth factors. Their proliferation and synthesis of matrix is essential for scar formation at sites of myocardial infarction, cardiac fibrosis, and is often complicated by cardiac hypertrophy. CF also respond to changing environments in pathophysiological conditions by modulating integrin expression. CF culture has been widely used as a model to study the cardiac matrix remodeled by physiological (exercise) and pathological (hypertension) stressors.HCFaa from Gentaur Research Laboratories are isolated from the human heart. HCF-aa are cryopreserved at secondary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HCF-aa are characterized by immunofluorescent method with antibody to fibronectin. HCF-aa are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HCF-aa are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Cardiac Fibroblasts-Fetal Atrial

ABC-TC3538 1 vial Ask for price
Description: Cardiac fibroblasts (CF) provide structural support for cardiac myocytes and are responsible for extracellular matrix synthesis in the heart during growth and pathophysiological conditions. CF are an important cellular component of myocardial responses to injury and the source of paracrine growth factors. Their proliferation and synthesis of matrix is essential for scar formation at sites of myocardial infarction and cardiac fibrosis. CF cultures have been widely used as a model to study the cardiac matrix remodeling by physiological (exercise) and pathological (hypertension) stressors. CF also has been found to form electric coupling with myocytes through gap junctions exerting electrotonic influences on the cells. These electronic couplings are suggested to play an important role in genesis of complex fractionated atrial electrogram sites and thus are a perfect model for study of atrial fibrillation.HCF-fa from Gentaur Research Laboratories are isolated from the human fetal atrium. HCF-fa are cryopreserved at secondary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HCF-fa are characterized by immunofluorescence with antibody specific to fibronectin. HCF-fa are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HCF-fa are guaranteed to further expand for 15 population doublings under the conditions provided by Gentaur Research Laboratories.

Human Cardiac Fibroblasts-fetal atrial 

CSC-7818W One Frozen vial Ask for price

Immortalized Human Liver Fibroblasts - SV40

T9450 1x10^6 cells / 1.0 ml
EUR 3950

Human Primary Bladder Stromal Fibroblasts

T4162 5x10^5 cells / 1.0 ml Ask for price

Human iPSC Line from human dermal fibroblasts

CSC-00851L One Frozen vial Ask for price

Human Cardiac Fibroblasts-Adult Ventrical

ABC-TC3536 1 vial Ask for price
Description: The cardiac fibroblasts (CF) are the principal cell type of the heart. They provide structural support for cardiac myocytes and are responsible for extracellular matrix synthesis in the heart during growth and pathophysiological conditions. CF are an important cellular component of myocardial responses to injury and the source of paracrine growth factors. Their proliferation and synthesis of matrix is essential for scar formation at sites of myocardial infarction, cardiac fibrosis, and is often complicated by cardiac hypertrophy. CF also respond to changing environments in pathophysiological conditions by modulating integrin expression. CF culture has been widely used as a model to study the cardiac matrix remodeled by physiological (exercise) and pathological (hypertension) stressors.HCFav from Gentaur Research Laboratories are isolated from the human heart. HCF-av are cryopreserved at secondary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HCFav are characterized by immunofluorescent method with antibody to fibronectin. HCF-av are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HCF-av are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Immortalized Human Corneal Fibroblasts (IHCF)

T0578 1x106 cells / 1.0 ml
EUR 3950

Human Colon Cancer-Associated Fibroblasts

CSC-C2847 One Frozen vial Ask for price

Human Cardiac Fibroblasts-adult ventrical 

CSC-C4872L One Frozen vial Ask for price

Rat Lung Fibroblasts

ABC-TC4158 1 vial Ask for price
Description: Rat Primary Lung Fibroblasts from Gentaur are isolated from tissue of neonatal Sprague-Dawley Rats. Rat Primary Lung Fibroblasts are grown in T75 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Cells are negative for bacteria, yeast, fungi, and mycoplasma. Rat Primary Lung Fibroblasts are tested for expression of marker using the antibody of anti-FSP1/S100A4 by immunofluorescence staining and can be expanded by 3-6 passages at a split ratio of 1:2 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with fibroblast cultures include the assays of cell to cell interaction, PCR, Western blotting, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Rat Skin Fibroblasts

ABC-TC4217 1 vial Ask for price
Description: Rat skin fibroblasts, 2-week Wistar rat

Rat Vein Fibroblasts

ABC-TC4240 1 vial Ask for price
Description: Rat Primary Vein Fibroblasts from Gentaur are isolated from tissue of adult Sprague-Dawley Rats. Rat Primary Vein Fibroblasts are grown in T75 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Cells are negative for bacteria, yeast, fungi, and mycoplasma. Rat Primary Vein Fibroblasts are tested for expression of marker using the antibody of anti-FSP1/S100A4 by immunofluorescence staining and can be expanded by 2-4 passages at a split ratio of 1:2 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with fibroblast cultures include the assays of cell to cell interaction, PCR, Western blotting, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Human Brain Vascular Adventitial Fibroblasts

ABC-TC3525 1 vial Ask for price
Description: Human Brain Vascular Adventitial Fibroblasts from Gentaur are isolated from human brain vascular tissue. HBVAF are cryopreserved at first passage of primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HBVAF are characterized by spindle morphology and by immunofluorescent method with antibody to fibronectin. HBVAF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HBVAF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Immortalized Human Mammary Fibroblasts (HMF3A)

T0153 1x106 cells / 1.0 ml
EUR 3950

Immortalized Human Mammary Fibroblasts (HMF3S)

T0154 1x106 cells / 1.0 ml
EUR 3950

Immortalized Human Diploid Fibroblasts - hTERT

T1013 1x106 cells / 1.0 ml
EUR 2750

Immortalized Human Kidney Fibroblasts-SV40

CSC-I2121Z One Frozen vial Ask for price

Rat liver fibroblasts

ABC-TC4153 1 vial Ask for price
Description: Rat liver fibroblasts are isolated from tissue of 1-day-old neonatal Sprague–Dawley rats. Mouse liver fibroblasts are grown in T75 tissue culture flasks pre-coated with 0.2% gelatin for 1 hour and incubated in Culture Complete Growth Medium.

Dog liver Fibroblasts

cAP-d0010 1Frozen Vial
EUR 396

Human Pulmonary Artery Adventitia Fibroblasts

ABC-TC3773 1 vial Ask for price
Description: Fibroblasts are mesenchymal cells which derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies. This is mainly because they are one of easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. There is good evidence that fibroblasts in different parts of the body are intrinsically different. The pulmonary arterial vesculature responds to various insults with a characteristic pattern of remodeling that includes an increase in connective tissue in the medial layer of the vessel wall. One of the pathogenetic mechanisms involved is the functional derangements of vascular fibroblasts. Their proliferative response contributes to the adventitial thickening observed during the development of hypoxia-induced pulmonary hypertension. HPAAF from Gentaur Research Laboratories are isolated from human pulmonary artery. HPAAF are cryopreserved at passage one and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HPAAF are characterized by spindle morphology and by immunofluorescent method with antibody to fibronectin. HPAAF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HPAAF are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories.

Human Breast Carcinoma Associated Fibroblasts

ABC-TC5536 1 vial Ask for price
Description: CAFs reside within tumor tissue and serve various functions including suppression of immune responses to cancerous cells, support of tumor cell growth and enhancement of metastasis.Product is manufactured, tested and validated in an ISO 9001/ISO13485/CLIA certified facility.

Immortalized Human Gingival Fibroblasts- hTERT

T0026 1x106 cells / 1.0 ml
EUR 3950

Immortalized Human Neonatal Fibroblasts - hTERT

T0344 1x106 cells / 1.0 ml
EUR 2750

Human Primary Villous Mesenchymal Fibroblasts

T4112 5x10^5 cells / 1.0 ml Ask for price

Human Pulmonary Artery Adventitia Fibroblasts 

CSC-C4028X One Frozen vial Ask for price

Mouse Lung Fibroblasts

ABC-TC3931 1 vial Ask for price
Description: Mouse lung fibroblasts, 2-week ICR mouse

Rat Aortic Fibroblasts

ABC-TC4070 1 vial Ask for price
Description: Rat Primary Aortic Fibroblasts from Gentaur are isolated from tissue of neonatal Sprague-Dawley Rats. Rat Primary Aortic Fibroblasts are grown in T75 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Cells are negative for bacteria, yeast, fungi, and mycoplasma. Rat Primary Aortic Fibroblasts are tested for expression of marker using the antibody of anti-FSP1/S100A4 by immunofluorescence staining and can be expanded by 2-4 passages at a split ratio of 1:2 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with fibroblast cultures include the assays of cell to cell interaction, PCR, Western blotting, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Rat Artery Fibroblasts

ABC-TC4074 1 vial Ask for price
Description: Rat Primary Artery Fibroblasts from Gentaur are isolated from tissue of adult Sprague-Dawley Rats. Rat Primary Artery Fibroblasts are grown in T75 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Cells are negative for bacteria, yeast, fungi, and mycoplasma. Rat Primary Artery Fibroblasts are tested for expression of marker using the antibody of anti-FSP1/S100A4 by immunofluorescence staining and can be expanded by 2-4 passages at a split ratio of 1:2 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with fibroblast cultures include the assays of cell to cell interaction, PCR, Western blotting, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Rat Dermal Fibroblasts

ABC-TC4119 1 vial Ask for price
Description: Rat Dermal Fibroblasts (RDF) are derived from the dermis of normal Sprague Dawley rats. They are cryopreserved at first passage and can be cultured and propagated at least 8 population doublings.

Rat Kidney Fibroblasts

ABC-TC4147 1 vial Ask for price
Description: Rat kidney fibroblasts are isolated from tissue of 1-day-old neonatal Sprague–Dawley rats. Rat kidney fibroblasts are grown in T75 tissue culture flasks pre-coated with 0.2% gelatin for 1 hour and incubated in Culture Complete Growth Medium.

Rat Spleen Fibroblasts

ABC-TC4222 1 vial Ask for price
Description: Rat Primary Spleen Fibroblasts from Gentaur are isolated from tissue of neonatal Sprague-Dawley Rats. Rat Primary Spleen Fibroblasts are grown in T75 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Cells are negative for bacteria, yeast, fungi, and mycoplasma. Rat Primary Spleen Fibroblasts are tested for expression of marker using the antibody of anti-FSP1/S100A4 by immunofluorescence staining and can be expanded by 2-4 passages at a split ratio of 1:2 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with fibroblast cultures include the assays of cell to cell interaction, PCR, Western blotting, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Rat Uterus Fibroblasts

ABC-TC4237 1 vial Ask for price
Description: Rat uterus fibroblasts, 6-week Wistar rat

Human Cancer PrimaCell7: Esophageal Fibroblasts

2-96030 1 Kit Ask for price

Human Primary Periodontal Ligament Fibroblasts

T4075 5x10^5 cells / 1.0 ml
EUR 975

Immortalized Human Pulmonary Fibroblasts Cells

T0490 1x106 cells / 1.0 ml
EUR 2750

Immortalized Human Gingival Fibroblasts-SV40

CSC-I2120Z One Frozen vial Ask for price

Immortalized Human Pulmonary Fibroblasts Cells

CSC-I9127L One Frozen vial Ask for price

Human Skin PrimaCell: Normal Skin Fibroblasts

2-96103 1 Kit Ask for price

Mouse Aorta Fibroblasts

ABC-TC3912 1 vial Ask for price
Description: Mouse aorta fibroblasts, 2-week ICR mouse

Rabbit Lung Fibroblasts

ABC-TC4064 1 vial Ask for price
Description: Rabbit Primary Lung Fibroblasts from Gentaur are isolated from lung tissue of New Zealand White Rabbits. Rabbit Primary Lung Fibroblasts are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen. Rabbit Primary Lung Fibroblasts are negative for bacteria, yeast, fungi, and mycoplasma. Cells can be expanded for 3-6 passages at a split ratio of 1:3 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with cell cultures include the assay of cell to cell interaction, RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining, flow cytometry or generating cell derivatives for desired research applications.

Rat bladder fibroblasts

ABC-TC4080 1 vial Ask for price
Description: Rat bladder fibroblasts, 3-week Wistar rat

Rat Cardiac Fibroblasts

ABC-TC4105 1 vial Ask for price
Description: Rat Primary Cardiac Fibroblasts from Gentaur are isolated from tissue of adult Sprague-Dawley Rats. Rat Primary Cardiac Fibroblasts are grown in T75 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Cells are negative for bacteria, yeast, fungi, and mycoplasma. Rat Primary Cardiac Fibroblasts are tested for expression of marker using the antibody of anti-FSP1/S100A4 by immunofluorescence staining and can be expanded by 2-4 passages at a split ratio of 1:2 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with fibroblast cultures include the assays of cell to cell interaction, PCR, Western blotting, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Rat Mammary Fibroblasts

ABC-TC4167 1 vial Ask for price
Description: Rat Primary Mammary Fibroblasts from Gentaur are isolated from tissue of adult Sprague-Dawley Rats. Rat Primary Mammary Fibroblasts are grown in T75 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Cells are negative for bacteria, yeast, fungi, and mycoplasma. Rat Primary Mammary Fibroblasts are tested for expression of marker using the antibody of anti-FSP1/S100A4 by immunofluorescence staining and can be expanded by 2-4 passages at a split ratio of 1:2 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with fibroblast cultures include the assays of cell to cell interaction, PCR, Western blotting, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Rat Ovarian Fibroblasts

ABC-TC4187 1 vial Ask for price
Description: Rat Primary Ovarian Fibroblasts from Gentaur are isolated from tissue of adult Sprague-Dawley Rats. Rat Primary Ovarian Fibroblasts are grown in T75 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Cells are negative for bacteria, yeast, fungi, and mycoplasma. Rat Primary Ovarian Fibroblasts are tested for expression of marker using the antibody of anti-FSP1/S100A4 by immunofluorescence staining and can be expanded by 3-5 passages at a split ratio of 1:2 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with fibroblast cultures include the assays of cell to cell interaction, PCR, Western blotting, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Rat Thyroid Fibroblasts

ABC-TC4232 1 vial Ask for price
Description: Rat Primary Thyroid Fibroblasts from Gentaur are isolated from tissue of neonatal Sprague-Dawley Rats. Rat Primary Thyroid Fibroblasts are grown in T75 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Cells are negative for bacteria, yeast, fungi, and mycoplasma. Rat Primary Thyroid Fibroblasts are tested for expression of marker using the antibody of anti-FSP1/S100A4 by immunofluorescence staining and can be expanded by 2-4 passages at a split ratio of 1:2 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with fibroblast cultures include the assays of cell to cell interaction, PCR, Western blotting, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Rat Cardiac Fibroblasts

CP-R074 5×105 cells/vial
EUR 550
Description: Rat

Human Melanoma Carcinoma Associated Fibroblasts

ABC-TC5541 1 vial Ask for price
Description: Human Melanoma Cancer Associate Fibroblasts are isolated from malignant melanoma and cryopreserved at a low passage.Product is manufactured, tested and validated in an ISO 9001/ISO13485/CLIA certified facili

Human Lung PrimaCell1: Normal Lung Fibroblasts

2-96081 1 Kit Ask for price

Human Dermal Fibroblasts-fetal Feeder Cells

T2002 10^6 cells/1.0 ml
EUR 200

Monkey Liver Fibroblasts

ABC-TC3908 1 vial Ask for price
Description: Monkey Primary Liver Fibroblasts from Gentaur are isolated from tissue of Cynomolgus Monkey. Monkey Primary Liver Fibroblasts are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Monkey Primary Liver Fibroblasts are negative for bacteria, yeast, fungi, and mycoplasma. Cells can be expanded for 3-6 passages at a split ratio of 1:3 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with cell cultures include the assay of cell to cell interaction, RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining, flow cytometry or generating cell derivatives for desired research applications.

Rat Prostate Fibroblasts

ABC-TC4198 1 vial Ask for price
Description: Rat Primary Prostate Fibroblasts from Gentaur are isolated from tissue of adult Sprague-Dawley Rats. Rat Primary Prostate Fibroblasts are grown in T75 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Cells are negative for bacteria, yeast, fungi, and mycoplasma. Rat Primary Prostate Fibroblasts are tested for expression of marker using the antibody of anti-FSP1/S100A4 by immunofluorescence staining and can be expanded by 2-4 passages at a split ratio of 1:2 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with fibroblast cultures include the assays of cell to cell interaction, PCR, Western blotting, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Rat Tracheal Fibroblasts

ABC-TC4234 1 vial Ask for price
Description: Rat Primary Tracheal Fibroblasts from Gentaur are isolated from tissue of adult Sprague-Dawley Rats. Rat Primary Tracheal Fibroblasts are grown in T75 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Cells are negative for bacteria, yeast, fungi, and mycoplasma. Rat Primary Tracheal Fibroblasts are tested for expression of marker using the antibody of anti-FSP1/S100A4 by immunofluorescence staining and can be expanded by 2-4 passages at a split ratio of 1:2 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with fibroblast cultures include the assays of cell to cell interaction, PCR, Western blotting, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Rat Vascular Fibroblasts

ABC-TC4238 1 vial Ask for price
Description: Rat vascular fibroblasts, 2-week Wistar rat

Immortalized human Intestinal Fibroblasts-SV40

CSC-I2043Z One Frozen vial Ask for price

SV40-Human Intestine Fibroblasts

cAP-0206-SV40 1Frozen Vial
EUR 5049

GFP Expressing Human Lung Fibroblasts-Adults

GF13 1ml frozen Vial
EUR 850

Monkey Aortic Fibroblasts

ABC-TC3903 1 vial Ask for price
Description: Monkey Primary Aortic Fibroblasts from Gentaur are isolated from aortic tissue of Cynomolgus Monkey. Monkey Primary Aortic Fibroblasts are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Monkey Primary Aortic Fibroblasts are negative for bacteria, yeast, fungi, and mycoplasma. Cells can be expanded for 3-6 passages at a split ratio of 1:3 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with cell cultures include the assay of cell to cell interaction, RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining, flow cytometry or generating cell derivatives for desired research applications.

Monkey Dermal Fibroblasts

ABC-TC3905 1 vial Ask for price
Description: Monkey Primary Dermal Fibroblasts from Gentaur are isolated from tissue of Cynomolgus Monkey. Monkey Primary Dermal Fibroblasts are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Monkey Primary Dermal Fibroblasts are negative for bacteria, yeast, fungi, and mycoplasma. Cells can be expanded for 3-6 passages at a split ratio of 1:3 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with cell cultures include the assay of cell to cell interaction, RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining, flow cytometry or generating cell derivatives for desired research applications.

Rabbit Aortic Fibroblasts

ABC-TC4055 1 vial Ask for price
Description: Rabbit Primary Aortic Fibroblasts from Gentaur are isolated from aortic tissue of New Zealand White Rabbits. Rabbit Primary Aortic Fibroblasts are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen. Rabbit Primary Aortic Fibroblasts are negative for bacteria, yeast, fungi, and mycoplasma. Cells can be expanded for 3-6 passages at a split ratio of 1:3 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with cell cultures include the assay of cell to cell interaction, RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining, flow cytometry or generating cell derivatives for desired research applications.

Rat Embryonic Fibroblasts

ABC-TC4128 1 vial Ask for price
Description: Rat primary embryonic fibroblasts are isolated from day 13.5 embryos of Sprague-Dawley rats. Rat primary embryonic fibroblasts are grown in T75 tissue culture flasks pre-coated with 0.2% gelatin for 1 hour and incubated in Culture Complete Growth Medium.

Rat Lymphatic Fibroblasts

ABC-TC4164 1 vial Ask for price
Description: Rat Primary Lymphatic Fibroblasts from Gentaur are isolated from tissue of adult Sprague-Dawley Rats. Rat Primary Lymphatic Fibroblasts are grown in T75 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Cells are negative for bacteria, yeast, fungi, and mycoplasma. Rat Primary Lymphatic Fibroblasts are tested for expression of marker using the antibody of anti-FSP1/S100A4 by immunofluorescence staining and can be expanded by 2-4 passages at a split ratio of 1:2 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with fibroblast cultures include the assays of cell to cell interaction, PCR, Western blotting, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Rat Pulmonary Fibroblasts

ABC-TC4204 1 vial Ask for price
Description: The most abundant cell type in lung interstitium is fibroblasts. They resemble ordinary fibroblasts but have some distinguishing features, for example, they have long branching processes and gap junctions.

Mouse Cardiac Fibroblasts

CP-M074 5×105 cells/vial
EUR 580
Description: Mouse

Human Primary Osteoarthritis Synovial Fibroblasts

T5408 5 x 10^5/ 1.0 ml Ask for price

hTert-Human Intestine Fibroblasts

cAP-0206-hTert 1Frozen Vial
EUR 5049

Human Brain PrimaCell1: Normal Brain Fibroblasts

2-96013 1 Kit Ask for price

Human Eye PrimaCell3: Normal Corneal Fibroblasts

2-96059 1 Kit Ask for price

Human Heart PrimaCell3: Normal Heart Fibroblasts

2-96068 1 Kit Ask for price

The inducible molecule of fibroblast growth factor growth (FN14) plays a primary role in triggering tubular damage during the kidney injury of the septic tank (AKI). Here, we explore the mechanism underlying the deregulation of the FN14 of the septic tank Aki. We identify FN14 as a good faith target of Mir-19a, which directly binds to 3 ‘UTR of FN14 for the independent cylindromatosis repression (CYD), the dubiquitinase (Dub) downstream of Mir-19a, and antagonise. Thus the tubular tube induced by the cell apoptosis LPS.

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