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Metabolic Messengers: fibroblast growth factor 15/19
Fibrocoblast growth factor (FGF) 15 in the mouse and its human orthologist FGF19 (set rated FGF15 / 19) are intestinal hormones that control the homeostasis of bile acids and glucose during the transition from the Fed to the Gamening state. In addition to its central role in the regulation of the biliary homeostasis, FGF15 / 19 is now recognized as a cross-cutting metabolic coordinator at the crossroads of the gut, liver, brain and adipose white tissue. The dysregulation of the signaling FGF15 / 19 can contribute to the pathogenesis of several diseases affecting the axis of the gut liver and metabolic diseases.
Here we provide an overview of the current knowledge of the physiological roles of the entockin FGF15 / 19 and to highlight the commonalities and differences between the two orthologists. We also discuss the putative therapeutic potential in areas of unmet medical needs – such as cholesatic liver diseases and non-alcoholic steatohepatitis, for which FGF19 is tested in current clinical trials, as well as the possibility of using the FGF19 for the treatment of obesity and type II diabetes. Two patients have developed a trichiasis and a dry eye after FGFR inhibitor therapy. The treatments included artificial tears, life for life or cyclosporin and hair removal. A patient has stopped treatment with AZD4547 due to the severity of ocular adverse effects.
Neurotrophic factors have been considered promising potential for neuronal protection and regeneration and thus promote beneficial effects of kinesiological functions. They can be suspected of playing important roles in cellular transplant / fabric for various neuronal diseases. Clinical applications of such trophic factors to the central nervous system (CNS), however, caused problematic side effects due to distinctive bioactive properties. During the development of synthetic compounds reflecting the beneficial properties of the basic fibroblast growth factor (BFGF), we conducted filter candidates that stimulate to trigger the phosphorylation of intracellular tyrosine of the FGF receiver and leads to intracellular signaling. later in neurons.
The 4-Level Tumor Growth Factor Receiver provides for the effectiveness of lenvatinib in patients with advanced hepatocellular carcinoma
Objectives: Biomarkers optimizing the results of the treatment with lenvatinib in patients with advanced hepatocellular carcinoma remain to be put in place despite intense and global genomic research. Lenvatinib is characterized by its important inhibitory power for the fibroblast growth factor receiver (FGFR) 4 compared to earlier tyrosine kinase inhibitors. Thus, in this study, we focused on a simplified quantization of the FGFR4 in tumors as a potential predictive indicator.
Methods: According to cancer genome Atlas Data data set, the FGFR4 messenger RNA is largely overexpressed in hepatocellular carcinoma in the absence of genes alteration. The analysis of genes enrichment revealed that the aggressiveness of the tumor was closely linked to the FGFR4 level. To confirm the relationship between the benefits of lenvatinib and the tumor dependence along the FGFR4 way, we analyzed protein levels in tumors and peripheral blood obtained from 57 patients registered prospectively treated with lenvatinib.
Results: Positive immunohistochemistry (> 10% of tumor cells) For the FGFR4 in the biopsy samples before treatment is associated with a longer progression survival (2.5 vs 5.5 months, p = 0.01) and a favorable objective response rate (31% against 81%, p = 0.006). On the other hand, the concentration of FGFR4 soluble in the peripheral blood, measured by an immunosorbent dosage related to an enzyme, has not been associated with survival results because its fluctuations reflect hepatic fibrosis. An additional analysis of RNA sequencing using archival surgical samples (n = 90) suggested that FGFR4’s alternative RNA splicing in cancer may also explain this divergence.
Metabolic Messengers: fibroblast growth factor 15/19
YAP improves the proliferation of neuronal stem cells dependent on the FGF2 by induction of fibroblast growth factor receptor expression
The signaling path of the hippopotage regulates cell proliferation and organ growth and its activation is mainly reflected by YAP phosphorylation levels. We show here that YAP facilitates the proliferation of embryonic neural stem cells by raising their reactivity to the growth factor of Fibroblast 2 (FGF2), one of the main growth factors of neural stem cells, in vivo and in vitro. Western real-time and quantitative PCR analyzes revealed that FGFR1 FGFR4 receptors in FGFR4 has been significantly increased by YAP expression during FGF2 treatment, followed by increased marketing signal marketing. MAPK and AKT.
In addition, as evaluated by quantitative real-time PCR analyzes, YAP-induced FGFRS expression was deemed independent of Tead, and Taz, the other Yorki counterpart in the Drosophila Hippo signaling path, was noted possess an activity similar to YAP. Finally, the setting of the FGFR signaling activity in expressing YAP cells to effectively control the proliferative effects of YAP cell, suggesting that the increased proliferation of YAP express neural stem cells was mainly attributable to improved FGFR signaling. Our data indicates that YAP plays an important role in the regulation of neuronal stem cells by increasing the expression of the FGFR, then resulting in increased cell proliferation.
Human Fibroblasts-GFP Expressing
GFP07
Neuromics
500,000 Cells in T25 flask
EUR 1354
Immortalized Human Gingival Fibroblasts- hTERT
T0026
ABM
1x106 cells / 1.0 ml
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Immortalized Human Mammary Fibroblasts (HMF3A)
T0153
ABM
1x106 cells / 1.0 ml
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Immortalized Human Mammary Fibroblasts (HMF3S)
T0154
ABM
1x106 cells / 1.0 ml
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Immortalized Human Neonatal Fibroblasts - hTERT
T0344
ABM
1x106 cells / 1.0 ml
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Immortalized Human Pulmonary Fibroblasts Cells
T0490
ABM
1x106 cells / 1.0 ml
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Immortalized Human Corneal Fibroblasts (IHCF)
T0578
ABM
1x106 cells / 1.0 ml
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Immortalized Human Diploid Fibroblasts - hTERT
T1013
ABM
1x106 cells / 1.0 ml
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Human Cancer PrimaCell7: Esophageal Fibroblasts
2-96030
CHI Scientific
1 Kit
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Fibroblasts/Epithelial Cells Antibody
abx413035-02mg
Abbexa
0.2 mg
EUR 648
Fibroblasts/Epithelial Cells Antibody
abx413036-25ug
Abbexa
25 ug
EUR 300
FBS, Fibroblasts Optimized I
F0691-050
GenDepot
500ml
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Human Bladder PrimaCell2: Normal Bladder Fibroblasts
2-96008
CHI Scientific
1 Kit
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Human Brain PrimaCell1: Normal Brain Fibroblasts
2-96013
CHI Scientific
1 Kit
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Human Cervix PrimaCell2: Normal Cervical Fibroblasts
2-96045
CHI Scientific
1 Kit
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Human Eye PrimaCell3: Normal Corneal Fibroblasts
2-96059
CHI Scientific
1 Kit
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Human Heart PrimaCell3: Normal Heart Fibroblasts
2-96068
CHI Scientific
1 Kit
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Human Lung PrimaCell1: Normal Lung Fibroblasts
2-96081
CHI Scientific
1 Kit
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Human Lymph PrimaCell3: Normal Lymphatic Fibroblasts
2-96089
CHI Scientific
1 Kit
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Human Mouth PrimaCell: Normal Periodontal Fibroblasts
2-96090
CHI Scientific
1 Kit
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Human Skin PrimaCell: Normal Skin Fibroblasts
2-96103
CHI Scientific
1 Kit
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Immortalized Rat Embryonic Fibroblasts (18IM)
T0354
ABM
1x106 cells / 1.0 ml
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Fibroblasts/Epithelial Cells Antibody (RPE)
abx413037-100tests
Abbexa
100 tests
EUR 676
Fibroblasts/Epithelial Cells Antibody (RPE)
abx413038-25tests
Abbexa
25 tests
EUR 356
Human Cancer PrimaCell7: Esophageal Fibroblasts Growth Medium
9-46030
CHI Scientific
5 x 100 ml
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Human Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts
2-96051
CHI Scientific
1 Kit
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Human Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts
2-96083
CHI Scientific
1 Kit
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Human Bladder PrimaCell2: Normal Bladder Fibroblasts Growth Medium
9-46008
CHI Scientific
5 x 100 ml
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Human Brain PrimaCell1: Normal Brain Fibroblasts Growth Medium
9-46013
CHI Scientific
5 x 100 ml
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Human Cervix PrimaCell2: Normal Cervical Fibroblasts Growth Medium
9-46045
CHI Scientific
5 x 100 ml
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Human Eye PrimaCell3: Normal Corneal Fibroblasts Growth Medium
9-46059
CHI Scientific
5 x 100 ml
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Human Heart PrimaCell3: Normal Heart Fibroblasts Growth Medium
9-46068
CHI Scientific
5 x 100 ml
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Human Lung PrimaCell1: Normal Lung Fibroblasts Growth Medium
9-46081
CHI Scientific
5 x 100 ml
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Human Lymph PrimaCell3: Normal Lymphatic Fibroblasts Growth Medium
9-46089
CHI Scientific
5 x 100 ml
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Human Mouth PrimaCell: Normal Periodontal Fibroblasts Growth Medium
9-46090
CHI Scientific
5 x 100 ml
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Human Skin PrimaCell: Normal Skin Fibroblasts Growth Medium
9-46103
CHI Scientific
5 x 100 ml
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Human Cancer Tissue Preparation Buffer 7: Esophageal Fibroblasts
9-80030
CHI Scientific
1 x 100 ml
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Human Mouth Tissue Preparation Buffer: Normal Periodontal Fibroblasts
9-80090
CHI Scientific
1 x 100 ml
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Mouse Bladder PrimaCell2: Normal Bladder Fibroblasts
2-82007
CHI Scientific
1 Kit
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Mouse Brain PrimaCell1: Normal Brain Fibroblasts
2-82010
CHI Scientific
1 Kit
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Mouse Cervix PrimaCell2: Normal Cervical Fibroblasts
2-82024
CHI Scientific
1 Kit
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Mouse Eye PrimaCell3: Normal Corneal Fibroblasts
2-82039
CHI Scientific
1 Kit
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Mouse Heart PrimaCell3: Normal Heart Fibroblasts
2-82047
CHI Scientific
1 Kit
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Mouse Lung PrimaCell2: Normal Lung Fibroblasts
2-82065
CHI Scientific
1 Kit
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Mouse Lymph PrimaCell3: Normal Lymphatic Fibroblasts
2-82073
CHI Scientific
1 Kit
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Rat Bladder PrimaCell2: Normal Bladder Fibroblasts
2-82507
CHI Scientific
1 Kit
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Rat Brain PrimaCell1: Normal Brain Fibroblasts
2-82511
CHI Scientific
1 Kit
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Rat Cervix PrimaCell2: Normal Cervical Fibroblasts
2-82525
CHI Scientific
1 Kit
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Rat Eye PrimaCell3: Normal Corneal Fibroblasts
2-82540
CHI Scientific
1 Kit
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Rat Heart PrimaCell3: Normal Heart Fibroblasts
2-82548
CHI Scientific
1 Kit
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Rat Lung PrimaCell1: Normal Lung Fibroblasts
2-82564
CHI Scientific
1 Kit
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Rat Lymph PrimaCell3: Normal Lymphatic Fibroblasts
2-82572
CHI Scientific
1 Kit
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Mouse Anti Human Fibroblasts/Epithelial Cells Monoclonal Antibody,RPE
DMABT-49595MH
Creative Diagnostics
25 TEST
EUR 429
Human Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Medium
9-46051
CHI Scientific
5 x 100 ml
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Human Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts Growth Medium
9-46083
CHI Scientific
5 x 100 ml
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Human Bladder Tissue Preparation Buffer 2: Normal Bladder Fibroblasts
9-80008
CHI Scientific
1 x 100 ml
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Human Brain Tissue Preparation Buffer 1: Normal Brain Fibroblasts
9-80013
CHI Scientific
1 x 100 ml
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Human Cervix Tissue Preparation Buffer 2: Normal Cervical Fibroblasts
9-80045
CHI Scientific
1 x 100 ml
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Human Eye Tissue Preparation Buffer 3: Normal Corneal Fibroblasts
9-80059
CHI Scientific
1 x 100 ml
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Human Heart Tissue Preparation Buffer 3: Normal Heart Fibroblasts
9-80068
CHI Scientific
1 x 100 ml
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Human Lung Tissue Preparation Buffer 1: Normal Lung Fibroblasts
9-80081
CHI Scientific
1 x 100 ml
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Human Lymph Tissue Preparation Buffer 3: Normal Lymphatic Fibroblasts
9-80089
CHI Scientific
1 x 100 ml
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Human Skin Tissue Preparation Buffer 3: Normal Skin Fibroblasts
9-80103
CHI Scientific
1 x 100 ml
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Human Airway PrimaCell4: Normal Bronchial and and Tracheal Fibroblasts
2-96004
CHI Scientific
1 Kit
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Immortalized Mouse Embryonic Cystic Fibrosis Fibroblasts-Myc
T0253
ABM
1x106 cells / 1.0 ml
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Immortalized Mouse Embryonic Cystic Fibrosis Fibroblasts-SV40
T0257
ABM
1x106 cells / 1.0 ml
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Immortalized Mouse Embryonic Cystic Fibrosis Fibroblasts-Ras
T0258
ABM
1x106 cells / 1.0 ml
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Immortalized Bcl-x Mouse Embryonic Fibroblasts - SV40T
T0749
ABM
1x106 cells / 1.0 ml
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Mouse Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts
2-82031
CHI Scientific
1 Kit
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Mouse Lung PrimaCell4: Normal Pulmonary Artery Fibroblasts
2-82067
CHI Scientific
1 Kit
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Rat Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts
2-82532
CHI Scientific
1 Kit
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Rat Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts
2-82566
CHI Scientific
1 Kit
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Human Embryo Tissue Preparation Buffer 2: Normal Fetal Dermal Fibroblasts
9-80051
CHI Scientific
1 x 100 ml
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Human Lung Tissue Preparation Buffer 3: Normal Pulmonary Artery Fibroblasts
9-80083
CHI Scientific
1 x 100 ml
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Kidney Dissociation System 5 (Fibroblasts), Mouse and Rat
4-29295
CHI Scientific
ea
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Rat Bladder PrimaCell2: Normal Bladder Fibroblasts Growth Medium
9-25007
CHI Scientific
5 x 100 ml
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Rat Brain PrimaCell1: Normal Brain Fibroblasts Growth Medium
9-25011
CHI Scientific
5 x 100 ml
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Rat Cervix PrimaCell2: Normal Cervical Fibroblasts Growth Medium
9-25025
CHI Scientific
5 x 100 ml
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Rat Eye PrimaCell3: Normal Corneal Fibroblasts Growth Medium
9-25040
CHI Scientific
5 x 100 ml
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Rat Heart PrimaCell3: Normal Heart Fibroblasts Growth Medium
9-25048
CHI Scientific
5 x 100 ml
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Rat Lung PrimaCell1: Normal Lung Fibroblasts Growth Medium
9-25064
CHI Scientific
5 x 100 ml
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Rat Lymph PrimaCell3: Normal Lymphatic Fibroblasts Growth Medium
9-25072
CHI Scientific
5 x 100 ml
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Mouse Bladder PrimaCell2: Normal Bladder Fibroblasts Growth Medium
9-32007
CHI Scientific
5 x 100 ml
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Mouse Brain PrimaCell1: Normal Brain Fibroblasts Growth Medium
9-32010
CHI Scientific
5 x 100 ml
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Mouse Cervix PrimaCell2: Normal Cervical Fibroblasts Growth Medium
9-32024
CHI Scientific
5 x 100 ml
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Mouse Eye PrimaCell3: Normal Corneal Fibroblasts Growth Medium
9-32039
CHI Scientific
5 x 100 ml
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Mouse Heart PrimaCell3: Normal Heart Fibroblasts Growth Medium
9-32047
CHI Scientific
5 x 100 ml
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Mouse Lung PrimaCell2: Normal Lung Fibroblasts Growth Medium
9-32065
CHI Scientific
5 x 100 ml
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Mouse Lymph PrimaCell3: Normal Lymphatic Fibroblasts Growth Medium
9-32073
CHI Scientific
5 x 100 ml
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Human Airway PrimaCell4: Normal Bronchial and and Tracheal Fibroblasts Growth Medium
9-46004
CHI Scientific
5 x 100 ml
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Heart Dissociation System 11 (Cardiomycytes,Fibroblasts), Mouse and Rat
4-20281
CHI Scientific
ea
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Rat Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Medium
9-25032
CHI Scientific
5 x 100 ml
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Rat Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts Growth Medium
9-25066
CHI Scientific
5 x 100 ml
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Mouse Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Medium
9-32031
CHI Scientific
5 x 100 ml
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Mouse Lung PrimaCell4: Normal Pulmonary Artery Fibroblasts Growth Medium
9-32067
CHI Scientific
5 x 100 ml
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Mouse Bladder Tissue Preparation Buffer 2: Normal Bladder Fibroblasts
9-80121
CHI Scientific
1 x 100 ml
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Mouse Brain Tissue Preparation Buffer 1: Normal Brain Fibroblasts
9-80124
CHI Scientific
1 x 100 ml
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Mouse Cervix Tissue Preparation Buffer 2: Normal Cervical Fibroblasts
9-80138
CHI Scientific
1 x 100 ml
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Mouse Eye Tissue Preparation Buffer 3: Normal Corneal Fibroblasts
9-80153
CHI Scientific
1 x 100 ml
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Mouse Heart Tissue Preparation Buffer 3: Normal Heart Fibroblasts
9-80161
CHI Scientific
1 x 100 ml
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Mouse Lung Tissue Preparation Buffer 2: Normal Lung Fibroblasts
9-80179
CHI Scientific
1 x 100 ml
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Mouse Lymph Tissue Preparation Buffer 3: Normal Lymphatic Fibroblasts
9-80187
CHI Scientific
1 x 100 ml
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Rat Bladder Tissue Preparation Buffer 2: Normal Bladder Fibroblasts
9-80214
CHI Scientific
1 x 100 ml
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Rat Brain Tissue Preparation Buffer 1: Normal Brain Fibroblasts
9-80218
CHI Scientific
1 x 100 ml
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Rat Cervix Tissue Preparation Buffer 2: Normal Cervical Fibroblasts
9-80232
CHI Scientific
1 x 100 ml
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Rat Eye Tissue Preparation Buffer 3: Normal Corneal Fibroblasts
9-80247
CHI Scientific
1 x 100 ml
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Rat Heart Tissue Preparation Buffer 3: Normal Heart Fibroblasts
9-80255
CHI Scientific
1 x 100 ml
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Rat Lung Tissue Preparation Buffer 1: Normal Lung Fibroblasts
9-80271
CHI Scientific
1 x 100 ml
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Rat Lymph Tissue Preparation Buffer 3: Normal Lymphatic Fibroblasts
9-80279
CHI Scientific
1 x 100 ml
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Mouse Ariway PrimaCell3: Normal Bronchial and and Tracheal Fibroblasts
2-82003
CHI Scientific
1 Kit
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Rat Ariway PrimaCell3: Normal Bronchial and and Tracheal Fibroblasts
2-82503
CHI Scientific
1 Kit
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Human Airway Tissue Preparation Buffer 4: Normal Bronchial and and Tracheal Fibroblasts
9-80004
CHI Scientific
1 x 100 ml
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Lung Dissociation System 6 (Fibroblasts & Type II), Mouse and Rat
4-20316
CHI Scientific
ea
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Mouse Embryo Tissue Preparation Buffer 2: Normal Fetal Dermal Fibroblasts
9-80145
CHI Scientific
1 x 100 ml
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Mouse Lung Tissue Preparation Buffer 4: Normal Pulmonary Artery Fibroblasts
9-80181
CHI Scientific
1 x 100 ml
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Rat Embryo Tissue Preparation Buffer 2: Normal Fetal Dermal Fibroblasts
9-80239
CHI Scientific
1 x 100 ml
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Rat Lung Tissue Preparation Buffer 3: Normal Pulmonary Artery Fibroblasts
9-80273
CHI Scientific
1 x 100 ml
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Human Cancer PrimaCell7: Esophageal Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-47030
CHI Scientific
1 Set
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Cartilage Dissociation System 1 (Mesenchymal, Fibroblasts, Epithelial-like), Mouse and Rat
4-20231
CHI Scientific
ea
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Rat Ariway PrimaCell3: Normal Bronchial and and Tracheal Fibroblasts Growth Medium
9-25003
CHI Scientific
5 x 100 ml
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Mouse Ariway PrimaCell3: Normal Bronchial and and Tracheal Fibroblasts Growth Medium
9-32003
CHI Scientific
5 x 100 ml
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Human Bladder PrimaCell2: Normal Bladder Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-47008
CHI Scientific
1 Set
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Human Brain PrimaCell1: Normal Brain Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-47013
CHI Scientific
1 Set
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Human Cervix PrimaCell2: Normal Cervical Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-47045
CHI Scientific
1 Set
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Human Eye PrimaCell3: Normal Corneal Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-47059
CHI Scientific
1 Set
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Human Heart PrimaCell3: Normal Heart Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-47068
CHI Scientific
1 Set
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Human Lung PrimaCell1: Normal Lung Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-47081
CHI Scientific
1 Set
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Human Lymph PrimaCell3: Normal Lymphatic Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-47089
CHI Scientific
1 Set
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Human Mouth PrimaCell: Normal Periodontal Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-47090
CHI Scientific
1 Set
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Human Skin PrimaCell: Normal Skin Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-47103
CHI Scientific
1 Set
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Mouse Ariway Tissue Preparation Buffer 3: Normal Bronchial and and Tracheal Fibroblasts
9-80117
CHI Scientific
1 x 100 ml
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Rat Ariway Tissue Preparation Buffer 3: Normal Bronchial and and Tracheal Fibroblasts
9-80210
CHI Scientific
1 x 100 ml
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Human Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-47051
CHI Scientific
1 Set
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Human Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-47083
CHI Scientific
1 Set
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Human Airway PrimaCell4: Normal Bronchial and and Tracheal Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-47004
CHI Scientific
1 Set
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Rat Bladder PrimaCell2: Normal Bladder Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-26007
CHI Scientific
1 Set
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Rat Brain PrimaCell1: Normal Brain Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-26011
CHI Scientific
1 Set
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Rat Cervix PrimaCell2: Normal Cervical Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-26025
CHI Scientific
1 Set
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Rat Eye PrimaCell3: Normal Corneal Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-26040
CHI Scientific
1 Set
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Rat Heart PrimaCell3: Normal Heart Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-26048
CHI Scientific
1 Set
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Rat Lung PrimaCell1: Normal Lung Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-26064
CHI Scientific
1 Set
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Rat Lymph PrimaCell3: Normal Lymphatic Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-26072
CHI Scientific
1 Set
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Mouse Bladder PrimaCell2: Normal Bladder Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-33007
CHI Scientific
1 Set
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Mouse Brain PrimaCell1: Normal Brain Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-33010
CHI Scientific
1 Set
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Mouse Cervix PrimaCell2: Normal Cervical Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-33024
CHI Scientific
1 Set
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Mouse Eye PrimaCell3: Normal Corneal Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-33039
CHI Scientific
1 Set
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Mouse Heart PrimaCell3: Normal Heart Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-33047
CHI Scientific
1 Set
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Mouse Lung PrimaCell2: Normal Lung Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-33065
CHI Scientific
1 Set
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Mouse Lymph PrimaCell3: Normal Lymphatic Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-33073
CHI Scientific
1 Set
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Rat Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-26032
CHI Scientific
1 Set
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Rat Lung PrimaCell3: Normal Pulmonary Artery Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-26066
CHI Scientific
1 Set
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Mouse Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-33031
CHI Scientific
1 Set
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Mouse Lung PrimaCell4: Normal Pulmonary Artery Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-33067
CHI Scientific
1 Set
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Rat Ariway PrimaCell3: Normal Bronchial and and Tracheal Fibroblasts Growth Supplements with Serum (for 500 ml medium)
9-26003
CHI Scientific
1 Set
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The inducible molecule of fibroblast growth factor growth (FN14) plays a primary role in triggering tubular damage during the kidney injury of the septic tank (AKI). Here, we explore the mechanism underlying the deregulation of the FN14 of the septic tank Aki. We identify FN14 as a good faith target of Mir-19a, which directly binds to 3 ‘UTR of FN14 for the independent cylindromatosis repression (CYD), the dubiquitinase (Dub) downstream of Mir-19a, and antagonise . Thus the tubular tube induced by the cell apoptosis LPS.